About Doxepin

3.5 rating based on 136 ratings
Rating: 3.3 Reviews: 136
About Doxepin

Doxepin is used to treat depression and anxiety disorders. It suppresses restlessness, helps with sleep disorders and functional (not physical) organ disorders. It is also used in alcohol and drug withdrawal to suppress mild withdrawal symptoms.

What is the purpose of this ingredient?

  • relieve depression
  • Release fear
  • Reduce withdrawal symptoms in alcohol withdrawal
  • Reduce withdrawal symptoms on drug withdrawal
  • Promote sleep
  • relieve functional (non-physical) organ discomfort

This is how Doxepin works

Below you will learn more about the areas of application and the mode of action of Doxepin.
Please also read the information on the drug groups tri- and tetracyclic antidepressants, antidepressants, to which the active ingredient Doxepin belongs.

Areas of application of the active ingredient Doxepin

Doxepin is used to treat depression and anxiety disorders. It suppresses restlessness, helps with sleep disorders and functional (not physical) organ disorders. It is also used in alcohol and drug withdrawal to suppress mild withdrawal symptoms.

For the following application areas of Doxepin , in-depth information is available:

  • depression
  • anxiety disorders
  • nervous
  • alcohol dependence
  • sleep

Effect of Doxepin

Doxepin is one of the tricyclic antidepressants. It has pronounced calming, anxiolytic and mood-enhancing effects.

As an action mechanism for the effect in the brain an influence of the neurotransmitters serotonin and norepinephrine is assumed. Doxepin inhibits their reuptake into the cells, thus increasing their concentration in the brain and thus unfolding its positive effect.

Doxepin also inhibits the action of the tissue hormone histamine by blocking the H1 and H2 receptors. Doxepin was used to inhibit gastric juice secretion and the development of gastric ulcers under stress in different experimental settings.

Doxepin has a weak anticholinergic and antispasmodic effect both in the brain and in the rest of the body. Like other tricyclic antidepressants, it inhibits the conduction of the heart at high doses (slowing the heartbeat) and lowers the resistance within the blood vessels slightly (lowering blood pressure).

The following effects of doxepin have also been demonstrated in animal experiments: Effectiveness of analgesics, reduction of dependence on opioid analgesics, suppression of withdrawal symptoms in morphine dependence.

Potential Doxepin side effects may include:

Doxepin used to treat the following diseases:

  1. Anna B. Barnes says:
    4.0 rating

    Doxepin for Anxiety disorders; Depression

    Citalopram: initial violent side effects: dizziness, dizziness, mud in the bud, increased anxiety, palpitations, sweating, loss of libido, no more orgasm possible Conclusion: side effects except for libido and orgasm problem resolved, drug works well !! Doxepin: No side effects, even in the early days. Conclusion: Recommended! Drug works well !! Lorazepam: at doses from 2 MG on an empty stomach Dizziness, dizziness, gait insecurity. Conclusion: always works, helps well, to recommend! Especially in the beginning with Citalopram together !!!

  2. Luis A. Elkins says:
    4.5 rating

    Doxepin for Sleep disorders; Depression

    hello, doxepin since 2005 every evening 75mg taken. the drug is great! one sleeps quietly and firmly. one takes many kilos, in my case more positive. in the beginning there were problems with the circulation and palpitations during movement. You should only take this medi ca 1-2 before going to sleep. When taking sollteman should definitely eat something because doxepin otherwise shows little effect. I had the feeling the more I had eaten something, the better it worked. but definitely recommended.

  3. Alicia G. Kruger says:
    2.0 rating

    Doxepin for Sleep disorders

    severe drowsiness, numbness in the legs, body tremors, gait disturbances, tachycardia, shaky legs. Persistent after stopping, also complaints that did not exist before taking (constant lurching, muscle twitching, high blood pressure, insomnia, head always dull and oppressive, I feel like half dead) who were not there before.Mute permanent damage to the nervous system. (Tardive dyskinesis )

  4. Gail J. Coffman says:
    3.0 rating

    Doxepin for Sleep disorders

    Dazed when getting up. – as if you were drunk Uncontrolled muscle contraction just before you fall asleep. Tremble. And that at only 5mg Doxepin daily

  5. Vicki G. Garcia says:
    4.0 rating

    After morphine, Lyrica, Tilidine etc I finally have something against the pain, which helps: 25mg Doxepin. Due to the strong side effects, I rarely trust in Doxepin ran. 5 days were the longest I endured. Side effects: Shortly after taking drowsiness, not necessarily unpleasant. Then I can sleep fast, but wake up very quickly, then begins a night of horror. Sleepless, restless, anxious to paranoid, if I can fall asleep, I only sleep at the minute, with the worst nightmares. The next day I’m muddy and listless, somehow wide. My nose is so dry that it hurts, I feel like I’m getting flu. Increased salivation, I think is good. Until now, after each intake, small abscesses have grown in my groin which, after weaning, quickly rise (pus or sac) or simply disappear. More inflamed pimples on the face. Weight gain I can not judge, I take the tablets too rarely I think. Habs today with 12.5 mg tried, I am not so dizzy, nose is dry and hurts, still helps well against the pain. Let’s see how the night is .. The side effects seem to be very different for this drug from person to person.

  6. Amy J. Petri says:
    4.0 rating

    Doxepin for Aggressiveness; Drive disorders; Sleep disorders; Depression

    I’ve been taking mirtazapine for over 4 years, often had intense dreams and did not hear the alarm clock if I got up very early. At some point I had 5 alarm clocks but mostly brought nothing! Then suddenly I always got those dreams of my ex, I was not over him at the time. These dreams came more and more often until I then only dreamed the same and I was at the end, thought the pain tears me and I thought only of these stressful dreams. Then my doctor prescribed me Doxepin, and the dreams have stopped, thank God. But I still did not hear the alarm clock. It was always a pain to get out of bed in the morning, I managed to be punctual at 8 o’clock in 5 years. After falling into a deep hole again, depri with no end, miserable mood, and these aggression I have, avoid crowds at the moment as I am internally freaked out when I am in it, can not endure at the moment when these strangers to me to come close. I would like to box them all away. Then I prescribed my doctor Elontril and I now for 8 days, I noticed that I forget to eat that is bad had many years ne eating disorder, in this case should not actually be taken but I have in the handle when I eat I hope that will go away with the loss of appetite. Now to the best effect, I was the whole week punctually at just before 7 o’clock in the morning out of the houseIt happened that I had a training this week and had to get out so early. After over 5 years, I finally managed to get up so early without any problems, just the hammer that is a huge success for me :)) If I could get rid of this irritability and could be relaxed Elontril would be my miracle, let’s see how it develops ,

  7. Brenda M. Brooks says:
    4.5 rating

    Doxepin for Depression

    Doxepin is an antifungal antidepressant that has a sleep-inducing effect. Sure it works for each person individually, I can only report from my experience. I took Doxepin 50 mg for 6 weeks in the evening, it was supposed to make me sleep-inducing, and it did quite well. I fell asleep quickly, but my dreams were very wild and I had a headache the next morning. In addition, I’ve gained eight kl in this time, even if I’m quite slim, I did not want to take it, because I did not know where the weight now ends. The only good thing was that I fell asleep very quickly, that’s all. My depression did not improve, but I think I should have taken this medicine longer. I dropped it off because of the weight and the headache.

  8. Howard E. Bartlett says:
    3.0 rating

    Doxepin for Psychosis; Depression

    I have been taking Zeldox and Doxepin for about 6 years, after a drug-induced psychosis. Getting started with Zeldox was a bit difficult because I was pretty tired and unfocused in the first few days! After two or three weeks my body got used to the medication relatively quickly. The acute symptoms of psychosis were then as good as gone already after 10 days! I take only 80 mg of Zeldox in the evening and am worried that if I do not take it 2 hours before going to bed I can not sleep. Have forgotten it a few times and then could not sleep the whole night, even if I took it later than at the usual time. However, I will try to sell it in the near future because I want to live completely drug-free, after I have been taking drugs for 6 years now and have not smoked for 5 years. Because every drug has side effects and I believe any continuous use has consequences that the drug manufacturers can not rule out !. The Doxepin I’m already on the slink and I suddenly realize that in the morning I am not so tired. Otherwise, if I did not work, I could stay in bed until 11:00 and daydream! I took Doxepin at 25 mg in the morning and 50 mg in the evening. Currently I am on 25 mg in the evening and in 10 days I hope to be 0. Then it’s the turn of the Zeldox. I will also reduce in 20 mg steps over 4 weeks. I am a little bit afraid that the psychosis could recur, because my doctor persuades me permanently that I should take this a lifetime, but as I said, it is not in my sense to take medications that are not necessarily vital for a lifetime. Nevertheless, I can at least recommend the Zeldox very much. It reliably fixes the symptoms of psychosis and is certainly important for several years after an acute psychotic attack!

    Side effects: Daytime tiredness
  9. Ruth J. Chavarria says:
    2.0 rating

    Doxepin for Sleep disorders

    At the beginning of taking daytime sleepiness. Only 1 tablet in the evening 1h. take before sleep.

    Side effects: Daytime tiredness
  10. Nancy T. Russo says:
    3.5 rating

    Doxepin for Depression

    Against the possible weight gain, I do more sports as before, which has a positive impact against the worsening of multiple sclerosis. Sometimes, however, increases doxipin fatigue and daytime fatigue.

  11. Wendy L. Albertson says:
    3.0 rating

    Doxepin for Borderline

    Mirtazapine: tiredness, hunger, no desire for sex, nightmares, gaining weight (in 8 years 63.5kg, can sleep again at 30mg Doxepin: fatigue, hunger, nightmares, weight gain, can sleep again 100mg Fluctin: increased drive, increased sweating, no longer fall so deep in Dep. 40mg In this overall package, I am reasonably … but the weight gain is serious, which somehow never stands still. But when I sit down, I have to hurt myself often and badly … so I prefer to take.However That’s just self-harm, just on installments.

  12. Susan A. Carter says:
    4.0 rating

    Doxepin for Depression

    I’m getting tired, but I still do not sleep through. I often wake up at night because I have a lot of pain. In addition, I promise after taking a very strong cravings for sweets. At the moment I can not show my love and have already gained 2 kg in 20 days. I feel dizzy in the morning, but I am not sure if this is not related to the other medis. Let’s see how it goes on.

  13. Franklin A. Brito says:
    4.5 rating

    Doxepin for Depression

    Hello, dear sufferer I have taken the drug in tablet form Doxepin for a long time, at the beginning it had caused a tremendous improvement in my mental state. I took 50 mg half an hour before going to bed, could sleep well, also did not always have the bad feelings and thoughts! But what struck me was my enormous weight gain and my deteriorated vision. Also circulatory problems and tachycardia, as well as dizziness I could watch with me. I do not necessarily want to advise against this drug, but it would be more helpful to have a conversation with a trained psychologist and to work out a balanced daily routine with stress and rest periods. But that costs … I wish you all a speedy recovery!

  14. Doris C. Orr says:
    2.5 rating

    Doxepin for Depression

    Hello I am new here in the forum, imagine me briefly before I am Sarah 21 years and suffer and anxiety disorder and depression, so I have been prescribed the drug Doxepin, I take it now exactly 7 weeks and on Monday I was at the doctor and there you have found a change in the ECG and I am now afraid that it is a bad thing I feel constantly tired with the drug and knocked off.

    Side effects: Circulatory problems; Fatigue