About Doxepin

3.5 rating based on 134 ratings
Rating: 3.3 Reviews: 134
About Doxepin

Doxepin is used to treat depression and anxiety disorders. It suppresses restlessness, helps with sleep disorders and functional (not physical) organ disorders. It is also used in alcohol and drug withdrawal to suppress mild withdrawal symptoms.

What is the purpose of this ingredient?

  • relieve depression
  • Release fear
  • Reduce withdrawal symptoms in alcohol withdrawal
  • Reduce withdrawal symptoms on drug withdrawal
  • Promote sleep
  • relieve functional (non-physical) organ discomfort

This is how Doxepin works

Below you will learn more about the areas of application and the mode of action of Doxepin.
Please also read the information on the drug groups tri- and tetracyclic antidepressants, antidepressants, to which the active ingredient Doxepin belongs.

Areas of application of the active ingredient Doxepin

Doxepin is used to treat depression and anxiety disorders. It suppresses restlessness, helps with sleep disorders and functional (not physical) organ disorders. It is also used in alcohol and drug withdrawal to suppress mild withdrawal symptoms.

For the following application areas of Doxepin , in-depth information is available:

  • depression
  • anxiety disorders
  • nervous
  • alcohol dependence
  • sleep

Effect of Doxepin

Doxepin is one of the tricyclic antidepressants. It has pronounced calming, anxiolytic and mood-enhancing effects.

As an action mechanism for the effect in the brain an influence of the neurotransmitters serotonin and norepinephrine is assumed. Doxepin inhibits their reuptake into the cells, thus increasing their concentration in the brain and thus unfolding its positive effect.

Doxepin also inhibits the action of the tissue hormone histamine by blocking the H1 and H2 receptors. Doxepin was used to inhibit gastric juice secretion and the development of gastric ulcers under stress in different experimental settings.

Doxepin has a weak anticholinergic and antispasmodic effect both in the brain and in the rest of the body. Like other tricyclic antidepressants, it inhibits the conduction of the heart at high doses (slowing the heartbeat) and lowers the resistance within the blood vessels slightly (lowering blood pressure).

The following effects of doxepin have also been demonstrated in animal experiments: Effectiveness of analgesics, reduction of dependence on opioid analgesics, suppression of withdrawal symptoms in morphine dependence.

Potential Doxepin side effects may include:

Doxepin used to treat the following diseases:

  1. Luis A. Elkins says:
    4.5 rating

    Doxepin for Sleep disorders; Depression

    hello, doxepin since 2005 every evening 75mg taken. the drug is great! one sleeps quietly and firmly. one takes many kilos, in my case more positive. in the beginning there were problems with the circulation and palpitations during movement. You should only take this medi ca 1-2 before going to sleep. When taking sollteman should definitely eat something because doxepin otherwise shows little effect. I had the feeling the more I had eaten something, the better it worked. but definitely recommended.

  2. Alicia G. Kruger says:
    2.0 rating

    Doxepin for Sleep disorders

    severe drowsiness, numbness in the legs, body tremors, gait disturbances, tachycardia, shaky legs. Persistent after stopping, also complaints that did not exist before taking (constant lurching, muscle twitching, high blood pressure, insomnia, head always dull and oppressive, I feel like half dead) who were not there before.Mute permanent damage to the nervous system. (Tardive dyskinesis )

  3. Gail J. Coffman says:
    3.0 rating

    Doxepin for Sleep disorders

    Dazed when getting up. – as if you were drunk Uncontrolled muscle contraction just before you fall asleep. Tremble. And that at only 5mg Doxepin daily

  4. Vicki G. Garcia says:
    4.0 rating

    After morphine, Lyrica, Tilidine etc I finally have something against the pain, which helps: 25mg Doxepin. Due to the strong side effects, I rarely trust in Doxepin ran. 5 days were the longest I endured. Side effects: Shortly after taking drowsiness, not necessarily unpleasant. Then I can sleep fast, but wake up very quickly, then begins a night of horror. Sleepless, restless, anxious to paranoid, if I can fall asleep, I only sleep at the minute, with the worst nightmares. The next day I’m muddy and listless, somehow wide. My nose is so dry that it hurts, I feel like I’m getting flu. Increased salivation, I think is good. Until now, after each intake, small abscesses have grown in my groin which, after weaning, quickly rise (pus or sac) or simply disappear. More inflamed pimples on the face. Weight gain I can not judge, I take the tablets too rarely I think. Habs today with 12.5 mg tried, I am not so dizzy, nose is dry and hurts, still helps well against the pain. Let’s see how the night is .. The side effects seem to be very different for this drug from person to person.

  5. Amy J. Petri says:
    4.0 rating

    Doxepin for Aggressiveness; Drive disorders; Sleep disorders; Depression

    I’ve been taking mirtazapine for over 4 years, often had intense dreams and did not hear the alarm clock if I got up very early. At some point I had 5 alarm clocks but mostly brought nothing! Then suddenly I always got those dreams of my ex, I was not over him at the time. These dreams came more and more often until I then only dreamed the same and I was at the end, thought the pain tears me and I thought only of these stressful dreams. Then my doctor prescribed me Doxepin, and the dreams have stopped, thank God. But I still did not hear the alarm clock. It was always a pain to get out of bed in the morning, I managed to be punctual at 8 o’clock in 5 years. After falling into a deep hole again, depri with no end, miserable mood, and these aggression I have, avoid crowds at the moment as I am internally freaked out when I am in it, can not endure at the moment when these strangers to me to come close. I would like to box them all away. Then I prescribed my doctor Elontril and I now for 8 days, I noticed that I forget to eat that is bad had many years ne eating disorder, in this case should not actually be taken but I have in the handle when I eat I hope that will go away with the loss of appetite. Now to the best effect, I was the whole week punctually at just before 7 o’clock in the morning out of the houseIt happened that I had a training this week and had to get out so early. After over 5 years, I finally managed to get up so early without any problems, just the hammer that is a huge success for me :)) If I could get rid of this irritability and could be relaxed Elontril would be my miracle, let’s see how it develops ,

  6. Brenda M. Brooks says:
    4.5 rating

    Doxepin for Depression

    Doxepin is an antifungal antidepressant that has a sleep-inducing effect. Sure it works for each person individually, I can only report from my experience. I took Doxepin 50 mg for 6 weeks in the evening, it was supposed to make me sleep-inducing, and it did quite well. I fell asleep quickly, but my dreams were very wild and I had a headache the next morning. In addition, I’ve gained eight kl in this time, even if I’m quite slim, I did not want to take it, because I did not know where the weight now ends. The only good thing was that I fell asleep very quickly, that’s all. My depression did not improve, but I think I should have taken this medicine longer. I dropped it off because of the weight and the headache.

  7. Howard E. Bartlett says:
    3.0 rating

    Doxepin for Psychosis; Depression

    I have been taking Zeldox and Doxepin for about 6 years, after a drug-induced psychosis. Getting started with Zeldox was a bit difficult because I was pretty tired and unfocused in the first few days! After two or three weeks my body got used to the medication relatively quickly. The acute symptoms of psychosis were then as good as gone already after 10 days! I take only 80 mg of Zeldox in the evening and am worried that if I do not take it 2 hours before going to bed I can not sleep. Have forgotten it a few times and then could not sleep the whole night, even if I took it later than at the usual time. However, I will try to sell it in the near future because I want to live completely drug-free, after I have been taking drugs for 6 years now and have not smoked for 5 years. Because every drug has side effects and I believe any continuous use has consequences that the drug manufacturers can not rule out !. The Doxepin I’m already on the slink and I suddenly realize that in the morning I am not so tired. Otherwise, if I did not work, I could stay in bed until 11:00 and daydream! I took Doxepin at 25 mg in the morning and 50 mg in the evening. Currently I am on 25 mg in the evening and in 10 days I hope to be 0. Then it’s the turn of the Zeldox. I will also reduce in 20 mg steps over 4 weeks. I am a little bit afraid that the psychosis could recur, because my doctor persuades me permanently that I should take this a lifetime, but as I said, it is not in my sense to take medications that are not necessarily vital for a lifetime. Nevertheless, I can at least recommend the Zeldox very much. It reliably fixes the symptoms of psychosis and is certainly important for several years after an acute psychotic attack!

    Side effects: Daytime tiredness
  8. Ruth J. Chavarria says:
    2.0 rating

    Doxepin for Sleep disorders

    At the beginning of taking daytime sleepiness. Only 1 tablet in the evening 1h. take before sleep.

    Side effects: Daytime tiredness
  9. Nancy T. Russo says:
    3.5 rating

    Doxepin for Depression

    Against the possible weight gain, I do more sports as before, which has a positive impact against the worsening of multiple sclerosis. Sometimes, however, increases doxipin fatigue and daytime fatigue.

  10. Wendy L. Albertson says:
    3.0 rating

    Doxepin for Borderline

    Mirtazapine: tiredness, hunger, no desire for sex, nightmares, gaining weight (in 8 years 63.5kg, can sleep again at 30mg Doxepin: fatigue, hunger, nightmares, weight gain, can sleep again 100mg Fluctin: increased drive, increased sweating, no longer fall so deep in Dep. 40mg In this overall package, I am reasonably … but the weight gain is serious, which somehow never stands still. But when I sit down, I have to hurt myself often and badly … so I prefer to take.However That’s just self-harm, just on installments.

  11. Susan A. Carter says:
    4.0 rating

    Doxepin for Depression

    I’m getting tired, but I still do not sleep through. I often wake up at night because I have a lot of pain. In addition, I promise after taking a very strong cravings for sweets. At the moment I can not show my love and have already gained 2 kg in 20 days. I feel dizzy in the morning, but I am not sure if this is not related to the other medis. Let’s see how it goes on.

  12. Franklin A. Brito says:
    4.5 rating

    Doxepin for Depression

    Hello, dear sufferer I have taken the drug in tablet form Doxepin for a long time, at the beginning it had caused a tremendous improvement in my mental state. I took 50 mg half an hour before going to bed, could sleep well, also did not always have the bad feelings and thoughts! But what struck me was my enormous weight gain and my deteriorated vision. Also circulatory problems and tachycardia, as well as dizziness I could watch with me. I do not necessarily want to advise against this drug, but it would be more helpful to have a conversation with a trained psychologist and to work out a balanced daily routine with stress and rest periods. But that costs … I wish you all a speedy recovery!

  13. Doris C. Orr says:
    2.5 rating

    Doxepin for Depression

    Hello I am new here in the forum, imagine me briefly before I am Sarah 21 years and suffer and anxiety disorder and depression, so I have been prescribed the drug Doxepin, I take it now exactly 7 weeks and on Monday I was at the doctor and there you have found a change in the ECG and I am now afraid that it is a bad thing I feel constantly tired with the drug and knocked off.

    Side effects: Circulatory problems; Fatigue
  14. Scott E. Kohut says:
    4.0 rating

    Doxepin for Withdrawal symptoms

    Hello dear readers. After I went to the doctor for 7 days of abstinence from marijuana because of withdrawal symptoms, because I could no longer sleep properly because of panic attacks, I got from the doctor because I was really very tired with the nerves 3x 2.5 mg Tavor and a prescription for the drug doxepin. My doctor advised me to take one of the tavor immediately, as this should take the fear immediately so that I can calm down and breathe again. To the Doxepin he said I should take 2-3 pieces spread over the day. When I was out of practice and in the pharmacy, I started to cry, because all in all, was too much for me. It had taken almost 5 minutes until I came back down to some extent (very high pulse with strong PANIC). and the nice lady in the pharmacy said with the Tavor I will get better very quickly. I still asked if you take them with water or something. She just said melt in the mouth (works on oral mucosa). The Doxepin was not there at that moment so she asked me to come back at about 13:30 to pick it up. On the way home I took the Tavor to me and it was a quick improvement (almost 10 minutes) Finally, I could sleep. A short time later I went to the pharmacy again to pick up said Doxepin. Over the day distributed I took then also 3 of these tablets to me. I was pretty tired of the whole and slept well too. The same day the same dose and against evening we went again I had a violent panic attack (strong tachy dizziness and unreal feeling) in spite of Doxepin did not go away let alone I came to rest. However, I had already reckoned with that, as it was stated in the leaflet that the drug only really gets its effect after 2 weeks of use. So I took another Tavor 2.5 mg and luckily it went away. When I woke up the next day I felt completely dizzy and dizzy my circulation went right down to my knees and this worried me so I decided to lower the dose to 50 mg. Of course, I discussed this with the doctor and he told me to stay at 1 25mg Dioxepin in the morning and a 25mg Dioxepin in the evening. The drug made me really physically bothered by dizziness to dizziness up to the feeling I could die because it has pressed me very strong on the heart. (In the back of the head continue the idea that could be normal because it was inside the supplement and it was 2 weeks for the true development) on the same evening so day 3 with the drug and a dose of 50 mg I went out of concern to the hospital because I was uncomfortable just because of the leaflet because it takes 2 weeks I decided then home to go and endure it (the circulatory problems were far from great and I was progressively worse). I decided in the morning after getting up to try out if I just took a high dose of Doxepin and took one of them Tablet a quarter and of it again a quarter so 1/8. I have to say that I have the night before, mind you no Tavor taken more because I know that this addict and my doctor said I should only in case of emergency when no longer works. Well the morning broke little sleep and strong drowsiness with circulatory problems determined the day, I took as described above from a 25 mg tablet only 1/8 and went to hot bathing to boost the circulation. I felt like the days before total on it I would have smoked 30 heads and a bottle of whiskey intus I tell you absolute disaster I did not manage the day really nothing. In the evening, because I got such a kind of circulatory collapse-like condition, I went to the hospital in the evening as a panic spread in me which is anything but beautiful and in my opinion came because of the drug. I told the doctor my ordeal and he measured my heart rate a rest pulse of 120 I had. I asked him how long about the drug in the body remain he said about 12 hours. Note that I had only taken 5 mg ca and it was really dirty. He then prescribed me another drug called Opipramol 20 pcs. In 50 mg dose and said I should take this before falling asleep to be able to sleep better. The later the evening the better I was because this Doxepin was finally out of my body. I finally got clear in my mind the circulatory problems disappeared and I was fine. I made myself something to eat and took just before going to sleep like Verodnet a tablet. It took a good 2 hours until I fell asleep but it is a very restful sleep because my girlfriend had to get out early it was barely 4 hours. But do not worry about dizziness circulation

  15. Ester G. Neilsen says:
    3.5 rating

    Doxepin for Aggressiveness; Borderline; Sleep disorders

    Taking Doxepin for 14 days now. Daily dose 150 mg. Initial side effects such as severe drowsiness, delirium and mental confusion. However, was certainly at a too high dosage. Doxepin got against my strong restlessness and tension conditions in the context of a borderline disorder and after taking a variety of drugs, I am currently very satisfied. I take the medicine 3 times a day and am now well through the day. So the effect is very good – so good that inexperienced patients may want to keep their hands off it, because it really does rejuvenate. But can, as above, also be at the height of the dosage. – Now to Promethazine (also known as Atosil): causes the same as above, ingestion by drop or high tablet presentation more complicated; Effect top; Side effects but not to be underestimated. Promethazine unfolds after taking 30 drops its effect on me only after 3-4 hours, while Doxepin strikes already after 1 hour. The latter is longer lasting and gentler; Promethazine is more effective in one stroke and is not noticeable after a short time (apart from the side effects such as dullness and muscle relaxation). I would therefore recommend Promethazine only as a sleep aid, while Doxepin can be well incorporated into everyday life.