The following provides information on contraindications to the use of doxazosin in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).
When should Doxazosin not be used?
Doxazosin must not be used in case of hypersensitivity to the active substance or similar substances such as prazosin or terazosin. Doxazosin may be used only under special medical risk-benefit assessment
- on a low-salt diet or concomitant use of diuretics
- when water accumulates in the lungs due to changes in the heart valves (aortic or mitral stenosis)
- in cardiac muscle weakness, for example, by pulmonary embolism
- in severe coronary heart disease
- in hepatic impairment
- in combination with agents that may cause prolonged effects, such as cimetidine.
- in children.
In the treatment of benign prostate enlargement, doxazosin may also be used only with careful medical consideration of the benefit and risk of:
- low blood pressure
- Drop in blood pressure in history
- Benign prostate enlargement with simultaneous congestion of the upper urinary tract, chronic urinary tract infection or bladder stones
- overflow incontinence
- advanced renal failure.
Doxazosin must not be used to treat hypertension in narrowing the esophagus, stomach and intestines.
What should you watch out for during pregnancy and lactation?
During pregnancy and lactation, doxazosin should not be used.
What should be considered in children?
The drug should not be used in children.
Warnings and Precautions
- Regular medical checks are important for treatment with the drug. Especially at the beginning of therapy, the blood pressure has to be monitored regularly.
- The medication should be used with extra caution by the physician in patients with hepatic impairment.
- The drug boosts the antihypertensive effect of other medicines for high blood pressure and erectile dysfunction.
- The drug may affect the ability to drive or operate machinery. This applies to a greater extent at the beginning of treatment as well as in conjunction with alcohol.
Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.