About Diclofenac

3.0 rating based on 135 ratings
Rating: 2.9 Reviews: 135
About Diclofenac

Description and principle of operation

The drug was first introduced in 1973 by the Swiss pharmaceutical company Novartis and has since gained popularity as one of the most effective nonsteroidal anti-inflammatory drugs.

Diclofenac is characterized by three types of action:

  • Anti-inflammatory
  • Antipyretic
  • Pain Reliever

Diclofenac is known for its particularly strong anti-inflammatory properties. Its antipyretic effect is also quite strong. Often the drug helps when other medications do not work. Although its analgesic effect is not so powerful, so the drug is more suitable for the management of pain syndrome of mild to moderate strength.

The mechanism of action of Diclofenac is based on the fact that it suppresses the synthesis of prostaglandins and cyclooxygenase – substances that play an important role in the processes of inflammation. As a result, such unpleasant symptoms of inflammation as pain and swelling decrease. Also, the drug has the ability to regulate immunity. With prolonged use, antiallergenic properties of Diclofenac are manifested. After taking the tablets, the active substance is quickly absorbed into the blood plasma, and from there it enters the synovial fluid located in the joints.


Diclofenac tablets are designed primarily to reduce the symptoms of inflammatory processes in diseases of the musculoskeletal system.

These include:

  • arthritis of various nature
  • rheumatoid soft tissue damage
  • osteoarthritis
  • bursitis
  • osteochondrosis
  • herniated intervertebral disc

The drug is successfully used to relieve a moderate or weak pain syndrome under such conditions as:

  • neuralgia
  • myalgia
  • proctitis
  • migraine
  • headache
  • toothache
  • postoperative pain
  • injuries

Also, the drug is used when:

  • inflammatory processes of the small pelvis
  • algodismenorea
  • complex therapy of infectious diseases of the respiratory system

Instructions for use

With post-traumatic and postoperative edema the patient can take the drug without consulting a doctor. In other cases, taking the medication is only possible after the doctor’s prescription. Do not engage in self-medication Diclofenac, because it has many side effects and contraindications, especially strongly manifested with prolonged therapy.

Food slows the absorption of the drug but does not prevent it. Therefore, if you need the fastest action of the drug, then the pill should be taken half an hour before meals. Otherwise, the tablets should be taken during or after a meal. The tablet should be swallowed without chewing and washed down with water.

Adults and children older than 15 years are recommended to take a tablet of 25-50 mg 2-3 times a day. The maximum daily intake for adults is 150 mg. With prolonged therapy and in mild cases, the dose can be reduced to 75 mg.

For tablets, the optimal daily dose is 100 mg. The course of treatment with tablets should not exceed two weeks.

Dosage is calculated individually, depending on the disease and age. It is not recommended to give 50 mg tablets to children.

Potential Diclofenac side effects may include:

Diclofenac used to treat the following diseases:


  1. Ester M. Troutman says:
    2.5 rating

    Diclofenac for Hüftschaden; Coronary heart disease

    Since 2002 I have a massive intolerance to all medicines, also homeopathic kind and also vitamin tablets. As soon as I take them for more than 3-4 days, I get a strong feeling of muscle weakness in the legs, severe pain in the shoulder, a headache, dizziness, sweats, high pulse. I feel very ill then. I would, however, urgently need to take pills. I have heart pills, hip problems, osteoporosis and strong nervous disorders. I was with all doctors, naturopaths etc. Who has these problems too and can help me. Best regards Monika

    Side effects: Sweats; Headache; Dizziness
  2. Ronnie J. Gilbert says:
    2.0 rating

    Stomach upset, suppresses hunger

    Side effects: Stomach pain
  3. Sandy J. Johnson says:
    3.0 rating

    Diclofenac for Hüftschaden; Disc prolapse

    I’ve been taking Diclofenac 100 for more than 20 years and can only say that it helped me a lot. In order to protect the stomach a little, I take the drug often in the form of suppositories, it also acts faster. Unfortunately, the effect has diminished in recent years probably due to habituation and stronger complaints, the effect of something.

    Side effects: No side effects
  4. Marilyn F. Slaven says:
    4.0 rating

    Because of very conscious diet, no nicotine, (almost) no alcohol, enough vegetables and fruits, for 10 years daily 150 mg diclofenac (from Stada), and always after the meal. No problem.

    Side effects: No side effects
  5. Marge L. Pacheco says:
    3.5 rating

    Diclofenac for Disc prolapse

    After spraying and tablets first fatigue, nausea and later insomnia. In addition, hot, red cheeks and glassy eyes.

    Side effects: Insomnia; Fatigue; Nausea
  6. Tony E. Hartley says:
    3.0 rating

    Diclofenac for Pain (acute)

    Use in weeks of inflammation in the hip joint -Ohrensenen-circulation problems-nausea -Insiduals -Albträume -Schüttelfrost -Fieber stomach cramps -breaking

  7. Thomas T. Stafford says:
    2.5 rating

    Diclofenac for Disc prolapse

    Nausea, feeling unwell. 3 days hardly bowel movement.

    Side effects: Nausea
  8. Malcolm T. Mosley says:
    4.0 rating

    Diclofenac for Pain (acute)

    Use in case of cervical spine suspected flatulence, diarrhea

    Side effects: Flatulence; Diarrhea
  9. Billy A. Bradford says:
    2.5 rating

    Violent, very painful intestinal cramps after the third day, with diarrhea

    Side effects: Intestinal cramps; Diarrhea