About Diclofenac

3.0 rating based on 135 ratings
Rating: 2.9 Reviews: 135
About Diclofenac

Description and principle of operation

The drug was first introduced in 1973 by the Swiss pharmaceutical company Novartis and has since gained popularity as one of the most effective nonsteroidal anti-inflammatory drugs.

Diclofenac is characterized by three types of action:

  • Anti-inflammatory
  • Antipyretic
  • Pain Reliever

Diclofenac is known for its particularly strong anti-inflammatory properties. Its antipyretic effect is also quite strong. Often the drug helps when other medications do not work. Although its analgesic effect is not so powerful, so the drug is more suitable for the management of pain syndrome of mild to moderate strength.

The mechanism of action of Diclofenac is based on the fact that it suppresses the synthesis of prostaglandins and cyclooxygenase – substances that play an important role in the processes of inflammation. As a result, such unpleasant symptoms of inflammation as pain and swelling decrease. Also, the drug has the ability to regulate immunity. With prolonged use, antiallergenic properties of Diclofenac are manifested. After taking the tablets, the active substance is quickly absorbed into the blood plasma, and from there it enters the synovial fluid located in the joints.


Diclofenac tablets are designed primarily to reduce the symptoms of inflammatory processes in diseases of the musculoskeletal system.

These include:

  • arthritis of various nature
  • rheumatoid soft tissue damage
  • osteoarthritis
  • bursitis
  • osteochondrosis
  • herniated intervertebral disc

The drug is successfully used to relieve a moderate or weak pain syndrome under such conditions as:

  • neuralgia
  • myalgia
  • proctitis
  • migraine
  • headache
  • toothache
  • postoperative pain
  • injuries

Also, the drug is used when:

  • inflammatory processes of the small pelvis
  • algodismenorea
  • complex therapy of infectious diseases of the respiratory system

Instructions for use

With post-traumatic and postoperative edema the patient can take the drug without consulting a doctor. In other cases, taking the medication is only possible after the doctor’s prescription. Do not engage in self-medication Diclofenac, because it has many side effects and contraindications, especially strongly manifested with prolonged therapy.

Food slows the absorption of the drug but does not prevent it. Therefore, if you need the fastest action of the drug, then the pill should be taken half an hour before meals. Otherwise, the tablets should be taken during or after a meal. The tablet should be swallowed without chewing and washed down with water.

Adults and children older than 15 years are recommended to take a tablet of 25-50 mg 2-3 times a day. The maximum daily intake for adults is 150 mg. With prolonged therapy and in mild cases, the dose can be reduced to 75 mg.

For tablets, the optimal daily dose is 100 mg. The course of treatment with tablets should not exceed two weeks.

Dosage is calculated individually, depending on the disease and age. It is not recommended to give 50 mg tablets to children.

Potential Diclofenac side effects may include:

Diclofenac used to treat the following diseases:


  1. Karen R. Newton says:
    3.0 rating

    Metformin: watery diarrhea (since ingestion) Tiredness, listlessness Diclofenac: no effect or side effect to notice neither pain nor inflammation go back

    Side effects: Listlessness; Fatigue; Diarrhea
  2. Sebastian E. Bills says:
    3.5 rating

    Diclofenac for Pain (joint)

    Due to severe shoulder pain doctor’s visit.Description of diclofenac 75, daily 2 tablets. After 2 days severe bleeding rectal.Short unconscious.On the 3rd day deposition of diclofenac and emergency hospitalization.Blood loss within 1.5 days about 3 liters.It was the highest mortal danger.Ca one week Intensivstation.Laut statement of the doctor treated it No chance of survival 2-3 hours later.

    Side effects: Bleeding
  3. Mark E. Price says:
    4.5 rating

    My dad had surgery on the pancreas 18 years ago. At that time it was very bad for him. Only because of a new study he survived. Since then, he was diabetic, no longer drinking alcohol and limiting smoking to 2-3 cigarettes a day. Over time, he also got blood thinners. Exactly one year ago my father died. On 20.12.2009 he took Dicolfenac. At night it came to stomach bleeding and thereby to a bloody bowel movement. This was not immediately noticed, but interpreted as diarrhea of a gastrointestinal flu. In the early morning then to the hospital. Immediately emergency surgery, because due to the blood thinners too much blood was lost and a part of the stomach was completely over. OP went well, but my father did not recover at the age of 69 and died on 23.12.2009. Based on the drug list of the pharmacy was found that my father has been prescribed the drugs for many months. My dad went to the doctor every week. Whether he got a proper examination there can not be said.

    Side effects: Bleeding; Bloody chair
  4. Eugenio C. Furlong says:
    2.5 rating

    Diclofenac for Arthrosis

    Good in effect. Ingested irregularly. When taking 10 days, intestinal bleeding. KH Result: Clear from Diclofenac. In MOMENT arcoxia plus pntoprazole. Effect is not nearly as good.

    Side effects: Intestinal bleeding
  5. James D. Sutton says:
    3.0 rating

    Diclofenac for Gout

    For pain in an acute gout attack only helps me Voltaren 50 Resinat. However, the side effects are serious. Headache, fatigue, mood low.

  6. Donna G. Toon says:
    5.0 rating

    Diclofenac for Inflammation

    I was prescribed Diclofenac 75SL prolonged-release tablets because of extensive inflammation around the wrist. The maximum dose was 150mg per day, divided into one intake in the morning and one in the evening. The drug was taken for 10 days without a break. In the first 2-3 days, I still felt relatively minor side effects: drowsiness, sometimes despite sufficient sleep, an increased feeling of fatigue; in addition stomach ache and a general malaise, which concerns the stomach. Thereafter, however, these symptoms worsened dramatically and I was about to stop taking the drug or try ibuprofen instead (which the doctor had suggested as an alternative). In addition, new, sometimes felt as severely restrictive side effects were added. Overall, the following symptoms appeared: severe stomach and intestinal cramps, constipation and diarrhea, flatulence, the constant feeling of having a lump in the throat, depressive moods, extreme irritability – as if you had too thin skin, headaches and pressure in the head, sometimes Nausea, slackness, hives. I would not take the drug a second time, especially as there seems to be more compatible alternatives.

  7. Edward L. Reichenbach says:
    2.0 rating

    Diclofenac for Pain (joint)

    Swelling of the face. Eyes (eyelid) area and mainly the lips

    Side effects: Face swelling
  8. Dan P. Hernandez says:
    5.0 rating

    Diclofenac for Pain (back)

    After taking a Diclofenac 100mg capsule at 07:30 it came from 08:30 to itchy skin on the hands and feet. At about the same time, the face, including the eyelids, is allowed to swell. At 09:00 followed by balance disorders and a drop in blood pressure could be measured from 140: 90 to 110: 70. From about 10: 00 improved the condition and it could be consulted a doctor. No other medicines were taken at the same time or in the last 24 hours before.

    Side effects: Face swelling
  9. Margie H. Coker says:
    2.0 rating

    ibuprofen I could see well tolerated, but I had diclo and novalgin strong stomach problems. Hair loss then came to unfortunately, as well as novalgin dizziness has occurred. Unfortunately, only Novalgin gave me some relief, and the combination with additional ibuprofen (2 pieces )during the day

    Side effects: Hair loss; Dizziness; Stomach pain
  10. Stanley K. Tackett says:
    3.5 rating

    Diclofenac for Tendinitis

    1 month after weaning increased and visible hair loss over several months.

    Side effects: Hair loss
  11. Glenn R. Musser says:
    3.0 rating

    Diclofenac for Pain (acute)

    Never again! Taken 2 times, after about 8 hours first side effects. The most severe abdominal pain and stomach cramps I’ve ever had. Vomiting and diarrhea without end! Cold sweat extreme.

  12. George L. White says:
    4.0 rating

    Have a tablet Diglo 75mg the evening after eating & amp; taken the next day after breakfast. After I was well all day and I had only moderate pain in the evening I went to bed as usual with the difference that I woke up in the morning at 5 o’clock with extreme stomach pain. The pain (as if the inners were pulled through the navel) was associated with cold sweat & amp; Nausea over 3 hours. After consulting my doc, I stopped taking the medicine and got a medicine to fix my stomach. I prefer to endure the pain in my shoulder as this again. HANDS OFF!

    Side effects: Cold sweat; Stomach pain; Nausea
  13. Rebecca E. Pollack says:
    3.0 rating

    Diclofenac for Tendinitis

    On the 3rd day of taking Diclofenac I got severe stomach and intestinal pain with cramps, diarrhea and depressive moods. As well as loss of appetite and headache. At night then still cold sweat! I do not recommend taking the tablets!

  14. Harold N. Hardeman says:
    3.0 rating

    Diclofenac for Pain (acute)

    Joint and tendon pain. Especially in the area of the ankles, knee joints and wrists. Low back pain and shoulder pain. Ankles swollen left and right. Languor. Due to the drug Diclofenac, the joint pain is alleviated a little, but swelling has been added since kuzem. Will talk to my doctor about it and discontinue the Medikamnet, in the hope that the side effects disappear.

    Side effects: Swelling
  15. Barbara R. Baxter says:
    5.0 rating

    I got Voltaren Doro for my strong neck pain because ibuprofen did not stick. On the first day, the tablet has neither side effects nor relief of pain. On the second day I took two pills, the pain got a little better, but my circulation dropped completely and I started to sweat terribly. My right arm was suddenly numb. After a few hours the spook was over. Then I did not take the tablets for several days. When I took two pills again in the morning I got terrible circulatory problems again, I could hardly put one foot in front of the other and my right arm became numb again. This was followed by a panic attack and heart stumbling. I will not take Voltaren in this life anymore.

    Side effects: Panic attacks; Sweat
  16. Carrie R. Baker says:
    3.0 rating

    Diclofenac for Arthrosis

    when taking Diclofenac I sweat much more than usual. even without load !!

    Side effects: Sweat