About Diclofenac

3.0 rating based on 135 ratings
Rating: 2.9 Reviews: 135
About Diclofenac

Description and principle of operation

The drug was first introduced in 1973 by the Swiss pharmaceutical company Novartis and has since gained popularity as one of the most effective nonsteroidal anti-inflammatory drugs.

Diclofenac is characterized by three types of action:

  • Anti-inflammatory
  • Antipyretic
  • Pain Reliever

Diclofenac is known for its particularly strong anti-inflammatory properties. Its antipyretic effect is also quite strong. Often the drug helps when other medications do not work. Although its analgesic effect is not so powerful, so the drug is more suitable for the management of pain syndrome of mild to moderate strength.

The mechanism of action of Diclofenac is based on the fact that it suppresses the synthesis of prostaglandins and cyclooxygenase – substances that play an important role in the processes of inflammation. As a result, such unpleasant symptoms of inflammation as pain and swelling decrease. Also, the drug has the ability to regulate immunity. With prolonged use, antiallergenic properties of Diclofenac are manifested. After taking the tablets, the active substance is quickly absorbed into the blood plasma, and from there it enters the synovial fluid located in the joints.


Diclofenac tablets are designed primarily to reduce the symptoms of inflammatory processes in diseases of the musculoskeletal system.

These include:

  • arthritis of various nature
  • rheumatoid soft tissue damage
  • osteoarthritis
  • bursitis
  • osteochondrosis
  • herniated intervertebral disc

The drug is successfully used to relieve a moderate or weak pain syndrome under such conditions as:

  • neuralgia
  • myalgia
  • proctitis
  • migraine
  • headache
  • toothache
  • postoperative pain
  • injuries

Also, the drug is used when:

  • inflammatory processes of the small pelvis
  • algodismenorea
  • complex therapy of infectious diseases of the respiratory system

Instructions for use

With post-traumatic and postoperative edema the patient can take the drug without consulting a doctor. In other cases, taking the medication is only possible after the doctor’s prescription. Do not engage in self-medication Diclofenac, because it has many side effects and contraindications, especially strongly manifested with prolonged therapy.

Food slows the absorption of the drug but does not prevent it. Therefore, if you need the fastest action of the drug, then the pill should be taken half an hour before meals. Otherwise, the tablets should be taken during or after a meal. The tablet should be swallowed without chewing and washed down with water.

Adults and children older than 15 years are recommended to take a tablet of 25-50 mg 2-3 times a day. The maximum daily intake for adults is 150 mg. With prolonged therapy and in mild cases, the dose can be reduced to 75 mg.

For tablets, the optimal daily dose is 100 mg. The course of treatment with tablets should not exceed two weeks.

Dosage is calculated individually, depending on the disease and age. It is not recommended to give 50 mg tablets to children.

Potential Diclofenac side effects may include:

Diclofenac used to treat the following diseases:


  1. Jan K. Fleming says:
    2.5 rating

    Diclofenac for Cervical thoracic lumbar spine syndrome

    I got skin bleeding, open wounds in the mouth and at the last intake are swollen in my palate and larynx. According to my doctor have developed an allergy to this drug. Have gotten sleep problems, but they are not yet resolved. Whether that has something to do with the active ingredient, no one can answer me.

  2. Ann M. Hong says:
    2.5 rating

    Diclofenac for Pain (acute)

    For years Ibuprofen was prescribed for HWS syndrome. These have triggered heart rhythm disorders. After I told the doctor, he prescribed me something very good. Diclofenac. One tablet then took me to the hospital. Great. We have great doctors. Woman is always only fed with painkillers. Cause of the pain does not matter, the main thing the Pharma is sponsored. Damage repaired, disposed of the rest of the pack.

  3. Donald K. Faulkner says:
    1.0 rating

    Diclofenac for Fibromyalgia

    Hello I understand everything. Take devil’s claw (tablets). I was free of all pain after 14 days. Have taken before Dyclovenac.

    Side effects: No side effects
  4. Manuela J. Palmer says:
    2.5 rating

    Diclofenac for Fibromyalgia; Disc prolapse; Pain (acute)

    Diclofenac was very much on my stomach, only went with stomach protection Omepazol and then no more! Beofenac is better tolerated, but has to pay even though liberation still share

    Side effects: No side effects
  5. Monica W. Albanese says:
    4.0 rating

    Diclofenac for Joint and muscle pain

    Voltaren taken as tablets. Already at the first intake, at night waking up due to shortness of breath, itching and tingling on the body. Especially in the hands. My face was completely swollen and my circulation collapsed. Then came the panic because I could not control my body anymore. My husband immediately drove me to the emergency room. I have not come to the drug yet. Since I suffer from a serious food intolerance and the symptoms are similar and emergency room is unfortunately normal for me. In another context Dolormin was taken for a headache. Only 30 min. later that same game with the addition of severe diarrhea. Again emergency department and from there it was clear that it is due to the drug, which is contained in both drugs.

  6. Harry J. Dyer says:
    4.0 rating

    Diclofenac for Hüftschaden

    Because of my hip dislocation, I have repeatedly been prescribed by my old family doctor Dicofenac. Unfortunately, I always suffered from the usual side effects such as flatulence, diarrhea, stomach ache, and now and then a little dizziness and itchy skin. My new family doctor has prescribed me to Dicolfenac a stomach protection. Then the stomach ache, bloating and diarrhea were done. Conclusion: I can only recommend stomach protection

  7. Leonard S. Lester says:
    3.0 rating

    Diclofenac for Hws + lws syndrome; Arthrosis

    For all medicines used interactions with each other. Such as stomach, intestinal complaints, edema pain especially at night while lying, so belching. Treatment with Riopan * and Nexium mups * 2x 2omgund Pantozol * 40mg.

  8. Dian J. Watkins says:
    3.5 rating

    Diclofenac for Muscle tenseness

    I took Diclofenac 50mg over 3 years morning / noon / evening, then started breaking my bones. My metatarsus is broken 4 times a year, so it had to be operated on. At the hospital I was told that this comes from diclofenac because it is not suitable for long-term treatment and makes the bones rotten and brittle. Since I dropped her off, the problems have disappeared.

  9. Stephanie H. McManus says:
    3.0 rating

    Diclofenac for Muscle tenseness

    I applied the gel over a large area in the neck / neck area and on the thigh. After about 15 minutes, I got a dizziness was getting worse. In addition, tachycardia and diarrhea. Only after 4 hours did the symptoms disappear. So if incompatibility is also the gel with caution to enjoy!

    Side effects: Palpitations; Dizziness; Diarrhea
  10. Rebecca Q. Espinosa says:
    2.0 rating

    Diclofenac for Muscle distortion

    Taking one capsule in the morning. On the fourth day in the evening strong stomach cramps, the whole night diarrhea and on the following day recurrent cramps with cold sweat. General condition very impaired. The painkiller was discontinued. Consultation with the doctor is still pending.

    Side effects: Stomach cramps; Diarrhea
  11. Raymond L. Hinderliter says:
    3.0 rating

    Diclofenac for Muscle distortion; Pain (back)

    I took Diclofenac 1 x 2 Retardkapseln after breakfast and towards evening I got strong diarrhea, freezing, fatigue and felt totally uncomfortable.

    Side effects: Fatigue; Diarrhea
  12. Thomas C. Sines says:
    3.0 rating

    Diclofenac for Muscle distortion

    Strong headache especially at night and early morning. Was even awake. But the inflammation in the muscle got better. But it will settle after 1 day and 3 tablets because of the unpleasant headache

    Side effects: Headache
  13. Chester K. Breshears says:
    2.0 rating

    Diclofenac for Tendonitis

    eat then take !!! it does not look so gentle on the stomach !!!

    Side effects: Stomach complaints
  14. Robert M. Hong says:
    3.5 rating

    Diclofenac for Gout

    no side effects; the gout attack is passé after 2 days

    Side effects: No side effects