Diazepam contraindications and warnings


The following provides information on contraindications to the use of diazepam in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).

When should diazepam not be used?

Diazepam, like all benzodiazepines, should not be used with:

  • hypersensitivity to benzodiazepines
  • dependence on drugs, drugs and alcohol or poisoning with these substances
  • Myasthenia gravis
  • severe chronic respiratory distress, especially in acute worsening
  • sleep apnea syndrome
  • severe liver damage due to the risk of brain damage.

Particularly careful medical benefit-risk assessment and monitoring is required at

  • Disorders of movement caused by the diseased spinal cord or brain
  • elderly and debilitated patients
  • Patients with impaired liver and kidney function
  • Acute untreated intraocular pressure increase, for example in narrow-angle glaucoma (special form of the green star).

Note: Benzodiazepines such as diazepam are not recommended as a psychotic drug of choice and should not be used to treat depression or anxiety associated with depression alone.

Not all Stress, excitement and anxiety require therapy with medication. They are often sequelae of physical or mental illnesses and can be influenced by other measures or targeted treatment of the underlying disease.

What should you watch out for during pregnancy and lactation?

Diazepam and a major metabolite get over the nut cake to the unborn child. They can accumulate there, which can lead to overdosage in the child resulting in malformations and mental limitations.

If mothers receive benzodiazepines during pregnancy, in high doses or during childbirth during pregnancy, the children may experience withdrawal symptoms such as difficulty breathing, slack muscles, decreased body temperature and poor drinking. Therefore, diazepam should only be used during pregnancy if the doctor considers it necessary.

Diazepam and its metabolites pass into breast milk. Since the active ingredient of newborns is degraded much slower than by children or adults, it comes to breathing difficulties and dehydration. It should therefore not be breastfed or weaned when treated with Diazepam.

What should be considered in children?

Depending on in which dosage form diazepam is to be used, there are special hints for children:

  • Rectiols (for the use of the rectum) are not authorized for newborns and infants.
  • Children over the age of one may receive diazepam in Fom from tablets or drops.
  • Pills and suppositories can be given to children over the age of seven.
  • As a solution for injection diazepam should not be given to infants and children under four months of age. For older children, the dosage is based on body weight.

Warnings and Precautions

  • The drug can cause memory loss; It is therefore important to ensure a sufficient sleep time after ingestion.
  • If there is aggravation or aggressiveness after using the medicine, the doctor should stop the treatment.
  • At the end of treatment, the dose of the drug should gradually decrease (“creep”).
  • Concentration and responsiveness are compromised by the drug to the extent that driving a car, doing certain jobs and operating machinery are dangerous. This is especially true in conjunction with alcohol.

Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.