About Cymbalta

3.5 rating based on 205 ratings
Rating: 3.6 Reviews: 205
About Cymbalta

Duloxetine has four uses:

    • In doses from 20 to a maximum of 40 milligrams, the active substance is used in women for the treatment of moderate to severe urinary incontinence of the stress or stress type. In the case of stress incontinence, the urinary bladder closure is weakened. An increase in pressure, such as occurs when sneezing, coughing, laughing or carrying loads overwhelmed the closure and it comes to involuntary urine output. Stress incontinence, one of the most common types of urinary incontinence, is more common in women than in men. Pregnancy, natural births, connective tissue weakness and aging processes cause the disease.
    • In dosages of 30 to a maximum of 60 milligrams, the drug is used to treat generalized anxiety disorders.

At doses of 60 to a maximum of 120 milligrams, duloxetine is used to treat moderate to severe depression and

  • Nerve pain as part of a diabetes mellitus (diabetic polyneuropathy).

    What is the purpose of this ingredient?

    • Increase muscle tension of the bladder sphincter
    • Promote urinary bladder occlusion
    • Increase the resilience of the bladder sphincter
    • release anxiety
    • lighten depressive moods
    • Breastfeeding pain in diabetic neuropathy

 

This is how Duloxetine works

Below you will learn more about the fields of application and the mode of action of duloxetine.
Please also read the information on the drug groups antidepressants, selective serotonin norepinephrine reuptake inhibitors (sSNRI), to which the active ingredient duloxetine belongs.

Areas of application of the active substance duloxetine

Duloxetine has four uses:

    • In doses from 20 to a maximum of 40 milligrams, the active substance is used in women for the treatment of moderate to severe urinary incontinence of the stress or stress type. In the case of stress incontinence, the urinary bladder closure is weakened. An increase in pressure, such as occurs when sneezing, coughing, laughing or carrying loads overwhelmed the closure and it comes to involuntary urine output. Stress incontinence, one of the most common types of urinary incontinence, is more common in women than in men. Pregnancy, natural births, connective tissue weakness and aging processes cause the disease.
    • In dosages of 30 to a maximum of 60 milligrams, the drug is used to treat generalized anxiety disorders.

At doses of 60 to a maximum of 120 milligrams, duloxetine is used to treat moderate to severe depression and

  • Nerve pain as part of a diabetes mellitus (diabetic polyneuropathy).More detailed information is available on the following Duloxetine application areas:
    • depression
    • anxiety disorders
    • Pain (mild to moderate)
    • Pain (strong to very strong)
    • urinary incontinence

    Mode of action of duloxetine

    For the transmission of nerve stimuli messenger substances must be distributed between the individual nerve cells. The faster these messenger substances are absorbed back into the cells, the faster the nerve stimulation disappears. Agents that inhibit this reuptake result in an increase in nerve stimuli and body functions.

    Duloxetine is a combined inhibitor for the reuptake of the neurotransmitters serotonin and norepinephrine in the nerve cells. Duloxetine thus increases the concentration of serotonin and norepinephrine in different parts of the brain in a dose-dependent manner. This increased concentration reduces the effect of anxiety, depression, and nerve pain caused by diabetes. On the nerve messengers dopamine, histamine, adrenaline and acetylcholine, however, the drug has little influence.

    In animal experiments, an increased concentration of serotonin and norepinephrine in the lower part of the spinal cord leads to activation of the bladder sphincter muscle. In women, a similar mechanism is assumed, which under physical stress leads to a stronger closure of the urinary bladder during the storage phase of the urine. This may explain the effect of duloxetine in the treatment of urinary incontinence-related women.

 

Potential Cymbalta side effects may include:

Cymbalta used to treat the following diseases:

  1. Christopher R. Vincent says:
    3.5 rating

    Cymbalta for Bipolar disorder

    Sweats: Hair constantly wet to wet. The worst thing is sweating on the face and back. Dizziness, especially under stress. The feeling of getting a stroke. Extreme fatigue attacks. Fall asleep within seconds, when I feel there’s no blood left in the brain. Forgetfulness. Concentration problems. Amnesia. strong weight gain despite sports and diet.

  2. Georgia D. Robertson says:
    4.0 rating

    Nausea and drowsiness in the first three weeks. Then no more side effects and also the fear is gone and that after 26 years of complaints.

    Side effects: Nausea; Fatigue
  3. Maryjane J. Flores says:
    4.0 rating

    Cymbalta for Depression

    first taken in july 2005. in the last 6-7 months, a very strong decrease in concentration, and in conversation with other people. an extreme sleep need.

  4. Lauren D. Wells says:
    3.5 rating

    Cymbalta for Borderline

    Better tolerability than Tegretal and Citalopram. However, a very high need for sleep and motivation difficulties Since the conversion even sexual desire is present again.

    Side effects: Listlessness; Fatigue