Cosopt contraindications and warnings


The following provides information on contraindications to the use of timolol in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).

When should Timolol not be used?

The active substance timolol should not be used in:

  • hypersensitivity
  • Diseases of the heart such as pronounced weakness of the heart muscle, slow heart rate, low blood pressure and disturbances of the nerves in the heart.
  • Breathing disorders, such as those associated with bronchial asthma and bronchitis.
  • Nutritional disorders of the cornea of the eye.

The use of timolol in the eye can also lead to an uptake of the active substance into the blood and corresponding side effects. Therefore, the same treatment restrictions apply to this area of application as to intake.

What should you watch out for during pregnancy and lactation?

The use during pregnancy is recommended only after strict medical benefit-risk consideration.

The active substance timolol also passes into breast milk when applied to the eye. There may be serious harm to the baby. The use of timolol during breast-feeding therefore requires special medical care.

What should be considered in children?

Timolol has led to respiratory arrest in premature babies and newborns in isolated cases. Therefore, the active ingredient timolol should not be used in premature and newborns.

Since the active substance in newborns and infants, applied to the eye, can pass over into the whole body more than in adults and can thus reach higher concentrations in the blood, use should only be carried out with careful consideration of the benefit-risk balance and below medical supervision.

Warnings and Precautions

  • When using the drug on the eye, regular monitoring of intraocular pressure and the nature of the cornea is necessary.
  • The drug may also result in positive drug testing when used on the eye.
  • Signs of hypoglycaemia may be obscured by eye drops.
  • Also when applied to the eye, the active substance, even when used as intended, may affect the visual performance or the ability to react when driving or operating machinery.

Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.