Clonidine side effects

What side effects can clonidine have?

Below you will find the most important information about possible known side effects of Clonidine.
These side effects do not occur, but you can. Because every person reacts differently to medication. Please also note that the type and frequency of side effects may vary depending on the drug formulation (eg tablet, syringe, ointment).

Common side effects:
calming, tiredness, drowsiness, dry mouth.

Uncommon side effects:
skin reactions, itching, headache, dizziness, parotid gland pain, abnormal sensation, constipation, nausea and vomiting, circulatory problems, circulatory collapse tendency with change of position, circulatory disturbances of the hands (Raynaud’s syndrome), potency decrease, decrease of the sexual desire (libido), skin redness.

Rare side effects:
sleep disorders, depression, cognitive disorders, hallucinations, nightmares, confusion, pupil adjustment disorders, weight loss, mammary gland growth in men.

Very rare side effects:
Blood pressure increase, urinary bladder dysfunction.

Unexplained side effects:
heartbeat slowing, renal circulatory disturbances, increased cardiac arrhythmia, increased cardiac insufficiency, influence of certain laboratory tests (coomb test and liver function test).

When used on the eye following side effects are described:
Uncommon side effects:
tiredness, dry mouth, low blood pressure, dizziness, eye burning.

Rare side effects:
headache, nausea, blurred vision,
foreign body sensation.

Very rare side effects: constipation, abnormal sensations, sleep disorders, slow heartbeat.

What interactions does clonidine show?

Please note that the interactions may vary depending on the drug formulation of a drug (eg tablet, syringe, ointment).

Together with clonidine and beta-blockers as well as cardiac glycosides, cardiac arrhythmias and heartbeat slowing may occur.

Co-administration of clonidine and other antihypertensive agents such as diuretics, hydralazine, dihydralazine, nifedipine, captopril and guanethidine enhances the hypotensive effect. This also applies to the lowering of blood pressure by low-salt diets.

Tricyclic antidepressants, neuroleptics and tolazoline reduce blood pressure lowering by clonidine. This also applies to the simultaneous use of hypertensive or sodium and water-sparing substances, such as non-steroidal anti-inflammatory drugs.

Clonidine potentiates the action of brain-active, cushioning agents such as hypnotics and sedatives, as well as alcohol.

Potential Clonidine side effects may include: