The following provides information on contraindications to the use of Clomiphene in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).
When should Clomifene not be used?
Clomifene must not be used with
- Hypersensitivity to the active substance
- bleeding disorders
- unexplained uterine bleeding
- existing or previous severe liver diseases (such as liver inflammation, jaundice, Dubin-Johnson syndrome, Rotor syndrome, porphyria), at least as long as certain liver enzymes (transaminases) have not normalized.
- cancers of the pituitary gland or ovaries
- certain ovarian dysfunction.
- formation of cysts in the ovaries
- Endometriosis (uterine mucosal proliferation outside the uterus) involving the ovaries
- Visual disturbances (blurred vision, eye flicker and flicker, spotting or flashes of light).
After six months of use, the likelihood of pregnancy decreases significantly as the body gets used to clomiphene. For this reason, the drug should not be used for more than six monthly cycles.
What should you watch out for during pregnancy and lactation?
The use of clomiphene during pregnancy is not allowed. For safety’s sake, a menstrual period should be initiated before starting treatment with the drug. Under no circumstances may the active ingredient be taken after the ovulation has been triggered, as it can lead to disturbances in the hormone balance of the mother, which can damage the embryo. The drug must therefore be used for the last time on the ninth day of the monthly cycle.
It is unknown whether clomiphene passes into breast milk and thus into the baby. To avoid damage to the child should be weaned before treatment with the drug.
What should be considered in children?
The application of Clomifene excludes treatment of children with the active substance.
Warnings and Precautions
- Pregnancy must be avoided while taking Clomiphene.
- An enlargement of the ovaries during treatment should be monitored by medical check-ups.
- Reactivity may be impaired due to possible vision problems.
- Machine operation may be impaired.
- Traffic may be affected.
Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.