About Ciprofloxacin

3.5 rating based on 226 ratings
Rating: 3.6 Reviews: 226
About Ciprofloxacin

Form of release

The tablets covered with a cover.


1 tablet, coated, contains:
active substance: ciprofloxacin hydrochloride 250, 500 mg.

Pharmacological effect

Ciprofloxacin is a broad-spectrum antimicrobial agent from the group of fluoroquinolones. It is bactericidal. The drug inhibits the DNA enzyme of bacteria, as a result of which DNA replication and the synthesis of bacterial cell proteins are disturbed. Ciprofloxacin acts both on multiplying microorganisms, and on being in a rest phase.
Ciprofloxacin is active against gram-negative aerobic bacteria; intracellular pathogens; Gram-positive aerobic bacteria. The majority of staphylococci, resistant to methicillin, are resistant to ciprofloxacin.

Indications for use

  • respiratory tract;
  • ear, nose and throat;
  • kidney and urinary tract;
  • genital organs;
  • the digestive system (including the mouth, teeth, jaws);
  • gallbladder and bile ducts;
  • skin, mucous membranes and soft tissues;
  • musculoskeletal system.

Ciprofloxacin is indicated for the treatment of sepsis and peritonitis, as well as for the prevention and treatment of infections in patients with reduced immunity (with immunosuppressant therapy).

Dosing and Administration

The dose of Ciprofloxacin depends on the severity of the disease, the type of infection, the condition of the body, the age, weight and function of the kidneys in the patient. Recommended doses are usually: Ciprofloxacin in tablet form 250 mg and 500 mg for oral administration:
When infections of the urinary tract take the drug Ciprofloxacin 0.125 – 0.5 g 2 times a day, in more severe cases – to 0.75 g 2 times a day. The course of treatment is usually 5 to 15 days.
Diseases of the lower respiratory tract of medium severity – 250 mg, and in more severe cases 500 mg, 2 times a day;
For the treatment of gonorrhea, a single administration of Ciprofloxacin in a dose of 250-500 mg is recommended;
Gynecological diseases, enteritis and colitis with severe and high temperature, prostatitis, osteomyelitis – 500 mg 2 times a day (for the treatment of banal diarrhea can be used at a dose of 250 mg 2 times a day).
The drug should be taken on an empty stomach, washed down with a sufficient amount of liquid. Patients with severe renal dysfunction should be given a half dose of the drug. The duration of treatment depends on the severity of the disease, but treatment should always last at least two more days after the disappearance of the symptoms of the disease. Usually, the duration of treatment is 7-10 days.

Application in pregnancy and lactation

Ciprofloxacin is contraindicated in pregnancy and lactation (breastfeeding).

Special instructions

If a severe and prolonged diarrhea occurs during or after treatment with ciprofloxacin, the diagnosis of pseudomembranous colitis should be ruled out, which requires immediate discontinuation of the drug and the appointment of appropriate treatment.
During the treatment with Ciprofloxacin, it is necessary to provide a sufficient amount of fluid while observing normal diuresis.
During treatment with Ciprofloxacin, contact with direct sunlight should be avoided.

Patients with epilepsy, episodes of seizures in history, vascular diseases and organic brain damage due to the threat of developing side effects from the central nervous system Ciprofloxacin should be prescribed only for vital indications.
If severe and prolonged diarrhea occurs during or after treatment with ciprofloxacin, the diagnosis of pseudomembranous colitis should be ruled out, which requires immediate discontinuation of the drug and the appointment of appropriate treatment.
If pain occurs in the tendons or when the first signs of tendovaginitis appear, treatment should be discontinued because individual cases of inflammation and even rupture of tendons during treatment with fluoroquinolones are described.

Potential Ciprofloxacin side effects may include:







Ciprofloxacin used to treat the following diseases:

  1. Alma D. Shipley says:
    2.0 rating

    Ciprofloxacin for Urinary tract infection

    Three weeks ago, I had a strong urinary tract infection and was prescribed ciprofloxacin 250 mg. I took it all twelve hours for three days, but stopped after the sixth tablet (out of ten pills) in consultation with the attending physician for pain in the feet, muscle pain in the thighs, I also felt the infamous pain in the Achilles heels , Since the urinary tract infection was already banned, there were no further problems with the demolition. The doctor had not heard of such side effects yet. The side effects are then gone for the time being. However, I had spared myself the whole time. Although I went for a walk a few times, I did not feel anything except the rapid onset of tiredness of the feet. However, four days ago I was bowling. Not a good idea! Pain in both Achilles heel, Muscle pain in the right thigh, Pain in the right hip joint, Overload of the left shoulder, Back pain. Other side effects and after-effects have occurred again or the first time. What I notice when I work longer on the keyboard: Arthritis pain in the wrists and fingers and tendon pain on the left hand. Besides, extreme fatigue / drowsiness and the throat area is sore. Since all this worried me a lot because of irreversible damage, etc., I was in the pharmacy yesterday. I read on the internet that green-lipped mussel extract should be good for the synovial fluid. I also wanted to get some magnesium, calcium, vitamin E, selenium and potassium for muscles and tendons. I described to the pharmacist my situation. She advised against green lipped mussel extract, because the effect was not scientifically proven and instead she did something special for osteoarthritis patients; o) Although not cheap, what can I say: Two hours after taking the first ration, I have literally felt how everything regenerates slowly; o) health costs! Let’s see how it goes on. What I miss with this dietary supplement, however, is magnesium. That’s why I also throw in such a magnesium-potassium mixture from the supermarket. Furthermore, I do gentle gymnastics and massage both legs of the calf regularly from the knee to the heel (to stimulate blood circulation). Before, I have never had such problems with my joints and tendons. It regularly crunches the left knee and the left elbow, and the said hip joint has often hurt and a tendonitis I had often, but I have got all these things by self-prescribed gymnastics and healthy nutrition under control. So my current problems come clearly from this drug. So I think that Cipro deprives the body of nutrients and thereby attacks the tendons, joints and muscles. There was probably also some animal experiment with rats, in which it came out that especially the animals got thinner tendons through the drug, where there was a magnesium deficiency. If I need this drug again, because there is no alternative, I will Only take it with nutritional supplements that act on joints, tendons and muscles. Then I just have to take care that the intake takes place every few hours, as certain minerals make the medicine ineffective. I hope that I will not sustain any lasting damage and that one or the other weak point caused by the drug will be regenerated. Should I again need an antibiotic and I want to turn back to such a bone-eating carnivore quinolone, I will ask for an alternative.

    Side effects: Pain; Tendinitis; Muscle aches
  2. Jim D. Marcum says:
    2.0 rating

    Ciprofloxacin for Urinary tract infection

    I had presented with burn urine at my family doctor (in Holland, The Hague). After a short urine test, the family doctor came to the conclusion that there are no bacteria in the urine. Nevertheless, he prescribes me as a precaution 200mg Doxicyklin. 2 days later, I went to the emergency room in the Hieseigen hospital due to increased pain. At the hospital I got the Ciprofloaxine prescribed twice a day for 7 days. After 7 days I got muscle pain all over my body (but mainly in the legs and in the abdominal area.) Also my vision on the left eye was a bit tired, I do not know how it all turns out and if I can hope for an improvement After reading all this report about Ciprofloaxine, my family doctor said I should take the ciprofloaxine for another 7 days, which I refuse.

    Side effects: Muscle aches
  3. Matthew S. Gardner says:
    4.5 rating

    Ciprofloxacin for Epididymis inflammation

    Chronic joint complaints. Patient was formerly athletic. Quinolones cause irreversible connective tissue damage (e.g., tendons and cartilage) through chelate complexation with Mg 2+ ions. 4 years later, MRI shows no signs of cartilage damage. The damage is too small or the nuclear spin too inaccurate. The symptoms occurred about 4 weeks after the end of the therapy.

    Side effects: Joint pain
  4. Robert M. Bates says:
    4.5 rating

    Ciprofloxacin for Epididymis inflammation

    No bacteria were detected. Muscle weakness, fatigue, joint pain, maste, pleasure and listlessness, neither in the urine nor in the sperm. Doctor informed after the first pack. Comment that one what you want, etc. Ingestion was set by me after the described difficulties have strengthened at night Freeze then sweat again. No more confidence after this Rosskur.Über a tip, I would be grateful. with tormented greetings my Geb. 27.01 .44

  5. Theresa J. Goodell says:
    5.0 rating

    Ciprofloxacin for Chlamydia infection

    Tendon pain. Through a 6-week intake of a chronic tendonitis (quinolone-induced tendinopathy) carried by it. See also I also had severe joint pain, was very tired, constant mild nausea and tears of the mouth.

    Side effects: Fatigue; Nausea; Joint pain