Form of release
The tablets covered with a cover.
1 tablet, coated, contains:
active substance: ciprofloxacin hydrochloride 250, 500 mg.
Ciprofloxacin is a broad-spectrum antimicrobial agent from the group of fluoroquinolones. It is bactericidal. The drug inhibits the DNA enzyme of bacteria, as a result of which DNA replication and the synthesis of bacterial cell proteins are disturbed. Ciprofloxacin acts both on multiplying microorganisms, and on being in a rest phase.
Ciprofloxacin is active against gram-negative aerobic bacteria; intracellular pathogens; Gram-positive aerobic bacteria. The majority of staphylococci, resistant to methicillin, are resistant to ciprofloxacin.
Indications for use
- respiratory tract;
- ear, nose and throat;
- kidney and urinary tract;
- genital organs;
- the digestive system (including the mouth, teeth, jaws);
- gallbladder and bile ducts;
- skin, mucous membranes and soft tissues;
- musculoskeletal system.
Ciprofloxacin is indicated for the treatment of sepsis and peritonitis, as well as for the prevention and treatment of infections in patients with reduced immunity (with immunosuppressant therapy).
Dosing and Administration
The dose of Ciprofloxacin depends on the severity of the disease, the type of infection, the condition of the body, the age, weight and function of the kidneys in the patient. Recommended doses are usually: Ciprofloxacin in tablet form 250 mg and 500 mg for oral administration:
When infections of the urinary tract take the drug Ciprofloxacin 0.125 – 0.5 g 2 times a day, in more severe cases – to 0.75 g 2 times a day. The course of treatment is usually 5 to 15 days.
Diseases of the lower respiratory tract of medium severity – 250 mg, and in more severe cases 500 mg, 2 times a day;
For the treatment of gonorrhea, a single administration of Ciprofloxacin in a dose of 250-500 mg is recommended;
Gynecological diseases, enteritis and colitis with severe and high temperature, prostatitis, osteomyelitis – 500 mg 2 times a day (for the treatment of banal diarrhea can be used at a dose of 250 mg 2 times a day).
The drug should be taken on an empty stomach, washed down with a sufficient amount of liquid. Patients with severe renal dysfunction should be given a half dose of the drug. The duration of treatment depends on the severity of the disease, but treatment should always last at least two more days after the disappearance of the symptoms of the disease. Usually, the duration of treatment is 7-10 days.
Application in pregnancy and lactation
Ciprofloxacin is contraindicated in pregnancy and lactation (breastfeeding).
If a severe and prolonged diarrhea occurs during or after treatment with ciprofloxacin, the diagnosis of pseudomembranous colitis should be ruled out, which requires immediate discontinuation of the drug and the appointment of appropriate treatment.
During the treatment with Ciprofloxacin, it is necessary to provide a sufficient amount of fluid while observing normal diuresis.
During treatment with Ciprofloxacin, contact with direct sunlight should be avoided.
Patients with epilepsy, episodes of seizures in history, vascular diseases and organic brain damage due to the threat of developing side effects from the central nervous system Ciprofloxacin should be prescribed only for vital indications.
If severe and prolonged diarrhea occurs during or after treatment with ciprofloxacin, the diagnosis of pseudomembranous colitis should be ruled out, which requires immediate discontinuation of the drug and the appointment of appropriate treatment.
If pain occurs in the tendons or when the first signs of tendovaginitis appear, treatment should be discontinued because individual cases of inflammation and even rupture of tendons during treatment with fluoroquinolones are described.