About Celebrex

3.0 rating based on 29 ratings
Rating: 2.9 Reviews: 29
About Celebrex

The active substance celecoxib is used in irritation of joint wear (so-called activated arthrosis) as well as in joint inflammation (so-called chronic polyarthritis of the group of inflammatory rheumatic diseases) to relieve pain and reduce inflammatory stimuli. Celecoxib can also be used to alleviate the symptoms of inflammatory spinal column disease Bechterew.

What is the purpose of this ingredient?

  • Reduce symptoms of joint wear
  • Reduce symptoms of arthritis (polyarthritis)
  • Reduce joint irritation
  • Reduce symptoms of inflammatory spinal disease (Bechterew’s disease)

This is how Celecoxib works

Below you will learn more about the fields of application and the mode of action of celecoxib.
Please also read the information on the drug classes non-steroidal anti-inflammatory drugs, anti-inflammatory drugs, painkillers to which the active ingredient celecoxib belongs.

Areas of application of the active substance celecoxib

The active substance celecoxib is used in irritation of joint wear (so-called activated arthrosis) as well as in joint inflammation (so-called chronic polyarthritis of the group of inflammatory rheumatic diseases) to relieve pain and reduce inflammatory stimuli. Celecoxib can also be used to alleviate the symptoms of inflammatory spinal column disease Bechterew.

For the following application areas of Celecoxib , in-depth information is available:

  • arthritis
  • inflammatory rheumatic diseases

Mode of action of celecoxib

Celecoxib belongs to the group of non-steroidal anti-inflammatory drugs and belongs to the subgroup of selective (targeted) cyclooxigenase-2 inhibitors.

The cyclooxygenases are enzymes that, inter alia, initiate the formation of certain endogenous messengers, the prostaglandins. Most prostaglandins are involved in the development of inflammation and pain. If prostaglandin formation fails by inhibition of cyclooxygenase, inflammation will regress and pain will be alleviated.

But there are also prostaglandins that exert protective functions in the body. These are important, for example, to protect the gastric mucosa from harmful substances. Such prostaglandins are produced by the enzyme cyclooxigenase-1.

Drugs like most non-steroidal anti-inflammatory drugs, which inhibit both cyclooxigenase-1 and cyclooxigenase-2, relieve pain but also cause gastric ulcers, for example. The targeted cyclooxigenase-2 inhibitors, which include celecoxib, have virtually no side effect.

Potential Celebrex side effects may include:

Celebrex used to treat the following diseases:

  1. Karen P. Farrior says:
    2.5 rating

    Celebrex for Disc prolapse

    In case of long-term medication severe gastrointestinal disturbances despite gastric protector, weight gain (massive), severe edema.

    Side effects: Increase in weight
  2. Danielle B. McKean says:
    3.5 rating

    Celebrex for Arthritis

    I had joint pain, which disappeared when taking the medication, but were immediately felt again, if I had forgotten the medicine at short notice. However, I am constantly tired and have extremely (about 1 kg every month!) Increase, although I have not changed my eating habits. In consultation with the rheumatologist, I will now try other drugs.

    Side effects: Increase in weight; Fatigue
  3. Susan J. Bowlin says:
    4.0 rating

    Celebrex for Disc prolapse; Arthrosis; Pain (back)

    Ingestion of Celebrex 1 X daily Tbl. Medication weak, therefore increase after 3 months on the advice of the physician = 2 X daily 1 tablet After increasing to 2 X daily 1 = no pain in the hip / back more for it after approx. 10 days of pain in the entire lower abdomen mainly right and left. Severe flatulence, change of diarrhea and constipation The pain persists even after discontinuation (2 weeks ago) of Celebrex. The belly is soft. A doctor’s appointment & gt; Internist soon. (Note: Diclofenac was also not tolerated because of severe colic and diarrhea, gastritis)

    Side effects: Stomach pain
  4. Donna N. Kerr says:
    2.5 rating

    Celebrex for Pain (back)

    No improvement, more pain.

  5. Denise R. Hernandez says:
    3.5 rating

    Celebrex for Arthrosis

    I’ve had an Odisee on drug testing for three years now. The pain therapist gave me 4 Celebrex for testing and the pain was greatly reduced after taking the first capsule. Then I have another 20 so daily 1 tablet. From then on I felt better. I’m not completely free of pain, but life is much more bearable. About side effects, I can not report anything, I have to take more medication, because of Parkinson’s, high pressure and much more. In order to achieve a better compatibility I take in the morning 1 Omebeta 20KMR.

    Side effects: No side effects
  6. Lisa T. Vazquez says:
    1.5 rating

    Celebrex for Arthrosis

    No side effects noticed, effect was very good

    Side effects: No side effects
  7. Ruth H. Reily says:
    4.5 rating

    Celebrex for Rheumatism

    I have always been good at rheumatic spasms … no side effects ever

    Side effects: No side effects
  8. Susan A. Silber says:
    2.0 rating

    Celebrex for Pain (chronic)

    Had no success with my pain and no effect from diarrhea

  9. Gilbert R. Coffey says:
    2.0 rating

    Celebrex for Psoriatic arthritis; Rheumatism

    The drugs worked very fast. However, after the Mtx injection 2 days, I am not feeling well. My stomach also rebels now and then.

  10. Kristyn T. Ratliff says:
    3.5 rating

    Celebrex for Arthritis

    I took Celebrex in the morning and in the evening .. but discontinued due to increasing heart problems (was 25 years old) The heart problems have returned to normal. Take now as a substitute indomethacin and prednisolone Celebrex I took another test – shortly afterwards hestige Herzrüthmusstörrungen! Absolutely not recommended the Cox2 inhibitor !!

  11. Jane S. Armitage says:
    5.0 rating

    Celebrex for Arthritis

    because I can not tolerate NSAIDs, I was prescribed Cox-2 inhibitors. At Celebrex, I got my rule 2 days after receipt, even though it was just over. I started 3 attempts and always in another period and always the same result. At Arcoxia I got my rule the next day. Here I started 2 attempts. The rheumatologist smiled at my concerns. A telephone conversation with the Phamazeutin the company revealed that because of my myoma, these drugs have responded and I should not take this.

  12. Terry P. Weddle says:
    2.0 rating

    Celebrex for Pain (joint)

    Side effects did not occur-none / little effect on pain.

    Side effects: No side effects
  13. Brittany J. Crandall says:
    3.5 rating

    Celebrex for Pain (acute)

    Celebrex only helps for a longer period and is very gentle on the stomach. Vigantolettes are taken only once a day and the values rise quickly again. Maxalt helps only at the beginning of a migraine attack, when the headaches are already too strong Novaminsulfon is faster effective, since they are drops and get straight into the bloodstream. L-thyroxine is well tolerated and thyroid levels are fast within normal limits.

    Side effects: No side effects
  14. Patricia R. Moore says:
    2.0 rating

    Celebrex for Pain (acute)

    very good compatibility, hardly any side effects, efficient in efficacy

    Side effects: No side effects