Baclofen side effects

What side effects can baclofen have?

Below you will find the most important information about possible known side effects of baclofen.
These side effects do not occur, but you can. Because every person reacts differently to medication. Please also note that the type and frequency of side effects may vary depending on the drug formulation (eg tablet, syringe, ointment).

Very common:
drowsiness, blunting (especially at the beginning of treatment), nausea.

Common side effects:
depression, twinkling (euphoria), delusion, nightmares, confusion (especially in elderly patients), fatigue, drowsiness, will weakening, tremors, gait insecurity, headache, dizziness, sleep disorders, fatigue, respiratory disorders, eye tremors, Disturbances of serenity, blurred vision, palpitations, decreased cardiac output, low blood pressure, retching, vomiting, dry mouth, diarrhea, constipation, gastrointestinal disturbances, nausea, bladder emptying disorders (frequent urination, bedwetting, urinary compulsion), skin rash, sweating, muscle weakness, muscle pain. !!!

Rare side effects:
excitement, nervous discomfort, taste disorders,
abdominal pain, urinary retention, liver dysfunction, speech disorders, erectile dysfunction.

Very rare and isolated side effects:
Hypersensitivity reactions, acute brain dysfunction (with
EEG changes, disorientation, trembling, excitement and muscle spasms), mouth-facial twitching, lower body temperature, liver enzyme elevation (SGOT, SGPT).

Special features:
The occurrence of side effects is highly dose-dependent.

After several months of treatment, a sudden end to therapy may result in difficulty concentrating, confusion, agitation, delusions, seizures, epileptic seizures and a rise in body temperature.

What interactions does Baclofen show?

Please note that the interactions may vary depending on the drug formulation of a drug (eg tablet, syringe, ointment).

The effect of antihypertensive agents is enhanced when taken concurrently. Other soothing or muscle relaxants (muscle relaxants) are also enhanced in their effects. Even with drugs that reduce brain function (such as psychotropic drugs, sleeping pills, opioid painkillers, tricyclic and tetracyclic antidepressants), there may be a mutual increase in the effect. Levodopa and carbidopa (both medicines for Parkinson’s disease) increase the risk of delusions.

Under no circumstances may alcohol be consumed with baclofen, as the interactions with alcohol are unpredictable.

Because baclofen alters the liver enzyme levels in the blood, it can falsify appropriate tests.

Potential Baclofen side effects may include: