About Baclofen

3.5 rating based on 27 ratings
Rating: 3.7 Reviews: 27
About Baclofen

Baclofen can be used wherever muscle spasm is to be abolished. The active ingredient is effective for cramps caused by signals from the brain or spinal cord.

What is the purpose of this ingredient?

  • Release muscle cramps

This is how Baclofen works

Below you will learn more about the fields of application and the mode of action of Baclofen.
Please also read the information on the drug group muscle relaxants,
to which the active ingredient baclofen belongs.

Application of the active substance Baclofen

Baclofen can be used wherever muscle spasm is to be abolished. The active ingredient is effective for cramps caused by signals from the brain or spinal cord.

Such cramps with increased muscle resistance can occur, for example, in multiple sclerosis, spinal cord injury, polio or other paralysis symptoms.

Baclofen can be taken orally, for example in the form of tablets. In severe cases, it is injected into the spinal fluid (intrathecal).

For the following application areas of Baclofen , in-depth information is available:

  • Multiple Sclerosis

Effect of Baclofen

Baclofen belongs to the group of muscle relaxants. Like all drugs in this group, baclofen also relieves muscle cramps.

Faulty control mechanisms in the brain or spinal cord can be the cause of pathological muscle spasm. For example, certain nerves are constantly activated. These nerves transmit their signals to other nerves until the signal arrives at a muscle cell. This muscle then tenses. If the signals coming from the nerve cells do not diminish, a permanent spasm of the muscle causes a spasm.

Baclofen exerts its effects in the brain and spinal cord. The active substance
is chemically similar to the most important messenger substance (transmitter substance, neurotransmitter) in the central nervous system, gamma-aminobutyric acid (GABA). It inhibits the transmission of impulses between the nerves in the spinal cord, so that no signals are transmitted to the muscles. This inhibition takes place between different nerve cells, but not at the point of transmission between nerve and muscle.

Because baclofen generally curbs brain activity, the undesirable side effect is tiredness (sedation), somnolence, drowsiness, and a reduction in voluntary muscle power.

Potential Baclofen side effects may include:

Baclofen used to treat the following diseases:

  1. Donna L. Santos says:
    4.0 rating

    Initially dizziness, headache, circulatory disturbances, finger crunches, muscle aches. Side effects disappear after 5 to 6 weeks. Suppression of graving to 100% when used properly. Partially rich 35mg daily. A miracle cure for alcohol dependence. However, accompanying psychotherapy makes sense.

    Side effects: Headache; Muscle aches; Dizziness
  2. Elisabeth R. Smith says:
    4.5 rating

    Baclofen for Alcohol addiction

    I have been dependent on alcohol for 20 years, had long-term therapies. There were always dry phases (the longest was 3 years). Relapses then accumulated last year. Have now let me prescribe Bachlofen. Now take 15mg a day and have no addiction anymore. However, I would advise anyone who starts with Baclofen to go on an outpatient psychotherapy because it relieves addiction, but does not solve the problems that lead to it. I have no side effects.

    Side effects: No side effects
  3. Samuel H. Morin says:
    4.0 rating

    Baclofen for Alcohol addiction

    Hello, got a week ago Baclofen 10mg, it should reduce the addiction pressure and fix panic attacks, so addiction pressure is less, but the panic attacks are still there. Take 3x 10 mg a day. Side effect I have kein.Mal see how it goes forward

    Side effects: No side effects
  4. Jeff H. Smotherman says:
    2.5 rating

    Baclofen for Multiple sclerosis

    Tysabri I tolerate very well. Baclofen dura does not work so well when it is too warm (at night) but otherwise good.

    Side effects: No side effects
  5. Brandon E. King says:
    4.5 rating

    Baclofen for Alcohol addiction

    Tiredness as a side effect at the beginning. has lasted about 5 days. very good compatibility. daily medication 75 mg

    Side effects: Fatigue
  6. Carlos K. Squires says:
    4.5 rating

    Baclofen for Alcohol addiction

    My experience with Baclofen taking Baclofen is 10.02.2010 initially with 6.5mg / 6.5mg / 6.5mg slow high dosing to 25mg / 25mg / 25mg as final dosage 03.03.2010 and not as described in Olvier ants with up to 200 mg and more a day! Complete elimination of anxiety panic attacks and depression Reduction of cigarette consumption by up to 95% a day (also considered as a side effect) Absolutely no craving for alcohol !! Other sleep habits (I can now sleep through from 11.00 pm to 7.00 am previously, even in dry times at most 6 hours) Increased motivation and Elan side effect: In the beginning often tiredness and can not sleep, dizziness and frequent urination. Be the final dose completely disappeared. On 01.02.10, the drug manufacturers raised their prices by 51% for Baclofen! “… aspirin was never tested for headache. Nevertheless, everyone takes it. And unlike baclofen, side effects such as bleeding in the brain or in the gastrointestinal tract are known from aspirin. But alcoholism and its consequences kill about 200 people every day in Germany alone. And with such a deadly disease, we doctors have to make an ethical decision: should we keep patients suffering and dying? Or should we give them a drug that we know is safe by being an old drug? (Prof. Dr. Olivier Ants)

  7. Edgar M. Tolbert says:
    4.5 rating

    Baclofen for Alcohol addiction

    The first really helpful drug for maintaining a satisfied abstinence. I take 3×12.5mg daily and have since the first use no more interest in alcohol. The initial tiredness, especially in the evening, is tolerable and does not restrict me in any way.

    Side effects: Fatigue