Augmentin contraindications and warnings


The following provides information on contraindications to the use of amoxicillin in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).

When should not Amoxicillin be used?

Amoxicillin should not be used if the patient is suffering from general penicillin hypersensitivity. Hypersensitivity is more likely in people with allergies or asthma. Amoxicillin should be used only after careful consideration of the benefit / risk by the physician and under his control.

  • Patients with viral infections (for example, infectious mononucleosis, Pfeiffer glandular fever)
  • liver dysfunction
  • renal dysfunction
  • People who have a particular form of blood cancer (lymphocytic leukemia) because they are at an increased risk of rash when given the drug.

Special features:
If the active ingredients are taken as a tablet or juice, their effectiveness may be impaired if they are not absorbed into the body from the intestine due to nausea and vomiting or diarrhea.
If the liver or kidneys malfunction, the doctor must reduce the drug dose accordingly. The functions of these organs as well as the blood picture should be regularly checked by the doctor during the treatment.

What should you watch out for during pregnancy and lactation?

Although amoxicillin does not have a harmful effect on the unborn child or human use, the active substance should only be used in pregnancy on the express instructions of the doctor. In some cases, severe neoplasm has been observed after neonatal treatment of the mother.

The active substance passes into breast milk and can damage the intestinal flora of the child. As a result, the breastfed child may get diarrhea or contract yeast infections. If a treatment of the mother is necessary, should be weaned

What should be considered in children?

The active substance is basically suitable for use in children. Children under the age of twelve receive between 40 and 50 (in exceptional cases up to 100) milligrams of amoxicillin per kilogram of body weight per day, depending on the nature and severity of the infection.

Warnings and Precautions

  • At high dosages of the drug, the incorporated drug may form crystals and clog a bladder catheter.
  • For long-term treatment (longer than 14 days), liver and kidney function and blood counts should be monitored regularly.
  • The active substance may reduce the intake of hormonal contraceptives (pill) from the intestine and thus impair its effectiveness. Therefore, an additional, non-hormonal contraception (condom, pessary) is necessary while taking.
  • If severe diarrhea occurs during treatment, seek medical advice immediately.
  • The laboratory evidence of sugar or urobilinogen from the urine can be falsified by the drug.
  • Possible side effects may affect driving and operating machinery.

Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.