Amaryl contraindications and warnings


The following provides information on contraindications to the use of glimepiride in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).

When should Glimepiride not be used?

In the case of hypersensitivity to glimepiride or other active substances belonging to the group of sulfonylureas, the active substance may not be used. The same applies to hypersensitivity to sulfonamides (group of active ingredients against bacteria) and probenecid (active ingredient for uric acid lowering).

Furthermore, glucepiride should be avoided in patients with diabetes mellitus due to insulin deficiency (type 1 diabetes mellitus), in the case of a glucosan spasm, in the case of a sugar-related metabolic derailment and after removal of the pancreas.

Furthermore, glimepiride must not be administered in the case of liver dysfunction and renal impairment, as well as in the event of major operations, accidents and infections if post-aggression syndrome is to be expected. The same applies if a pregnancy is planned in the near future.

What should you watch out for during pregnancy and lactation?

Glimepiride should not be used during pregnancy or breast-feeding.

What should be considered in children?

Glimepiride is not for use in children and adolescents.

Warnings and Precautions

  • During treatment, the levels of sugar in the blood and urine should be checked regularly.
  • Regular medical check-up of liver and blood cell counts is necessary.
  • Hypoglycaemia may occur during therapy, especially if meals are taken at irregular intervals or fail altogether. In case of hypoglycaemia, the patient should immediately consume sugar, which means that the hypoglycaemia can usually be compensated quickly. If a severe case of low blood sugar occurs, you should consult a doctor. This also applies if the hypoglycaemia occurs frequently or lasts longer.
  • No alcohol should be drunk during treatment with the drug.
  • Visual disturbances can occur during treatment.
  • The drug can limit the ability to react and concentrate so much that driving a car, operating machinery and working without a secure hold are dangerous.

Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.