Alprazolam side effects

What side effects can Alprazolam have?

Below you will find the most important information about possible known side effects of Alprazolam.
These side effects do not occur, but you can. Because every person reacts differently to medication. Please also note that the type and frequency of side effects may vary depending on the drug formulation (eg tablet, syringe, ointment).

Occasional side effects:
gastrointestinal disorders, libido changes, skin reactions.

Rare side effects:
Respiratory dysfunction (especially at night).

Side effects without frequency indication:
drowsiness (also on the following day), attention reduction, responsiveness reduction (also on the following day), tiredness, feeling dampness, confusion, muscle weakness, movement disorders, movement insecurity, gait insecurity, tremor, headache, dizziness, blurred vision, weight change, Indigestion, bladder dysfunction, refrain from eating, blood prolactin excess, menstrual disorders, liver dysfunction (jaundice).

Special features:
Most side effects occur especially at the beginning of therapy and usually decrease during the course of treatment.

Alprazolam, like all benzodiazepines, can cause memory lapses for the period after application. To prevent it, one must first of all pay attention to a sufficient sleep duration of the patients after ingestion.

Subliminal depression can suddenly become apparent during the use of alprazolam.

The use of the drug may cause emotional and adverse reactions such as restlessness, irritability, aggressiveness, anger, nightmares, delusions, psychosis, inappropriate behavior and other behavioral disorders, especially in elderly patients or children. In such cases the doctor should stop the treatment.

Even the intended use of Alprazolam can lead to the development of mental and physical dependence. Especially with sudden termination of the therapy, withdrawal symptoms can occur and the improved symptoms come back stronger. It is therefore important to take slowly diminished doses until the treatment is discontinued.

Taking Alprazolam in the evening may reduce the ability to react, concentrate and remain exhausted the next morning.

Because of the risk of falling through the muscle-loosening effect, especially in older patients caution is warranted.

What interactions does alprazolam show?

Please note that the interactions may vary depending on the drug formulation of a drug (eg tablet, syringe, ointment).

Alprazolam and the following active ingredients increase their antagonizing effect on the brain:

  • sedatives and hypnotics, analgesics in general and especially opioid analgesics, which may lead to accelerated dependence development
  • Psychotropic drugs such as neuroleptics such as desipramine, imipramine and fluvoxamine, whose blood levels rise due to alprazolam
  • anxiolytics and antidepressants including lithium
  • antiepileptic
  • H1 antihistamines
  • Muscle relaxants whose muscle-relaxing effect is intensified

Substances that inhibit certain liver enzymes involved in the breakdown of alprazolam increase its effects. These include:

  • Gastric agents from the drug groups of H2 blockers such as cimetidine and the proton pump inhibitors such as omeprazole
  • Estrogen-progestin combinations for contraception (“pill”)
  • macrolide antibiotics such as erythromycin
  • fungicides such as ketoconazole and itraconazole or other imidazoles and triazoles

Medical attention should be taken with concomitant use of alprazolam and the antihypertensive drug diltiazem.

Alcohol should not be consumed during treatment with alprazolam, as this will alter the effects in an unpredictable manner is reinforced. Also, the ability to drive and the ability to operate machines, additionally affected by the combination.

Potential Alprazolam side effects may include: