About Actos

3.5 rating based on 26 ratings
Rating: 3.5 Reviews: 26
About Actos

Pioglitazone is used for the treatment of so-called senile sugar (type 2 diabetes mellitus), when the blood sugar level can be adjusted insufficiently due to diet and physical activity.

What is the purpose of this ingredient?

    Treat leftover
  • Reduce blood sugar levels in combination with other blood sugar levels

This is how Pioglitazone works

Below you will learn more about the fields of application and the mode of action of pioglitazone.
Please also read the information on the drug classes glitazone, oral hypoglycaemic agents, antidiabetics, to which the active ingredient pioglitazone belongs.

Application of the active substance pioglitazone

Pioglitazone is used for the treatment of so-called senile sugar (type 2 diabetes mellitus), when the blood sugar level can be adjusted insufficiently due to diet and physical activity.

Pioglitazone can be taken one by one, both as a first-line treatment and after other blood sugar levels have failed.
The drug can also be used in combination with other blood sugar levels (oral antidiabetics such as sulfonylureas and derivatives and metformin) !!!

Since February 2007, pioglitazone may also be combined with all forms of insulin therapy. The addition of pioglitazone usually lowers the amount of insulin required to such an extent that it requires a re-adjustment of the insulin by the physician.

For the following application areas of Pioglitazon , in-depth information is available:

  • Type 2 Diabetes Mellitus

Action of Pioglitazone

The active ingredient pioglitazone, in the same way as all glitazones, reduces the insulin resistance (insulin resistance) of the adipose tissue, the muscles and the liver and thus lowers the blood sugar level. In addition, pioglitazone can reduce the production of sugar in the liver and improve the utilization of sugar in the body, for example in the muscles. This also optimizes the sugar metabolism.

In addition to improving the effect of the body’s own insulin, pioglitazone also enhances the effect of insulin delivered. The onset of action of pioglitazone, which is about two to three weeks in single therapy, comes in the combination with insulin much faster. When taking pioglitazone, the patient may have to reduce his insulin dose by up to 30 percent to prevent hypoglycaemia. Manchnal it is even possible to sell the insulin completely. However, switching to the combination should only be under the control of a physician experienced in the treatment of diabetes and with frequent follow-up visits.

Potential Actos side effects may include:

Actos used to treat the following diseases:

  1. James B. Bailey says:
    3.5 rating

    Actos for Diabetes mellitus type i

    significant weight gain of 8 kg, more often heartache (stitches) and joint pain especially in the arms. Actos was discontinued and metformin should be taken instead (one tablet each after breakfast or after dinner). After 1 – 2 weeks the renal values should be checked.

  2. Derrick F. Johnson says:
    4.5 rating

    Actos for Diabetes mellitus type ii

    I have gained about 50 kg in 2 years, got extreme edema in the thighs, which in turn had to be treated with fursosemide. As an effect enhancer to the insulins NovoRapid and Levemir Actos -30 was not to beat! My daily insulin requirement dropped from about 200 I.E. Novorapid to ca.80 / 90 I.U. while the Levemir requirement remains unchanged at 3β I.E. stayed in the morning + evening. HbA1c was lowered from 10.5 to 8.5, which I rate as the success of Actos-30. Whether the strong weight gain on Actos -30 is due, is doubtful, rather I typed lack of exercise (am wheelchair user). Family doctor wants to sell Actos-30 because of the increased heart attack risk.

    Side effects: Edema; Increase in weight
  3. Charles C. Estes says:
    3.0 rating

    Actos for Diabetes mellitus type ii

    Initially, the blood values, taking into account the further drug intake of Eucreas 1000 were very positive and gone down from sober (morning 160 to 120). Now after about 6 months, constant weight gain of 10 kg in one month. Constant pain in the spine, nerve pain in the muscle of the thigh. The assumption of these flicks have something to do with the hip prosthesis. However, no changes to the cause were noted. I will now discontinue the drug Actos and see how much my pain and weight change are changing. (My diabetologist seems to do a study with these two drugs)

    Side effects: Back pain; Increase in weight
  4. John V. Huey says:
    3.5 rating

    Actos for Diabetes mellitus type ii

    Starting visual disturbance, blurred vision; Weight gain well 35Kg in the 5 years; Impotence and constantly tired, as well as mad pain in the large joints, especially the knee joints. Every way is too far and hurts. Enormous water retention in the lower legs. Sleep disorders; If it takes a long time to sleep at most 2 hours at a time and erectile dysfunction. On the whole side effects only become aware of through conversations with other patients, only then / now only read the leaflet. The treating diabetologist did not notice anything during the whole time. New doctor’s appointment is already, then he has to come up with something. I’m so sorry! Actually, I could have read the note from Actos 45 right away, but I followed the doctor’s instructions and took it nicely. Never again!

  5. Derick M. Nelson says:
    3.0 rating

    Hello, I would like to briefly inform you here of the side effects that I have experienced after 9 months of taking Actos 30mg. Actually I tolerated Actos well at the beginning. Then I got water retention on my hands and feet, itching, nausea, weight gain. fatigue

  6. William E. Tyler says:
    2.5 rating

    The constant tiredness is annoying, losing weight does not work, Frequently itching on the skin in all places, easy but annoying there just at times everywhere.

    Side effects: Itching; Fatigue
  7. Paul J. Larocque says:
    4.0 rating

    Actos for Diabetes mellitus type ii

    First, after about 7 days swelling of the forearms and hands with marked redness of the skin and increasing itching. After another 7 days breathlessness occurred during a brisk walk. This breathlessness intensified. I then discontinued the medication (without consulting a doctor). After about 10 days, the swelling and redness had disappeared. The shortness of breath unfortunately lasted about 2 weeks (decreasing).

  8. Gregory T. Hayes says:
    4.5 rating

    Actos for Diabetes mellitus type ii

    A transfer of my general practitioner to the Diabetologische focused practice brought a new drug setting within the ICT and me in 2008 for the first time with Actos 15 in contact. At the same time, the accompanying medication was adjusted to Metformin 500, later to Metformin 1000. Almost parallel, there was an inexplicable nausea, which even brought me out of bed once every night and into the bathroom in anticipation of a nausea that never came. I have even had this examined once with a gastroscopy, of course, without findings. However, the insulin resistance decreased very slowly – it turned a long-term (!?) A more stable blood sugar levels. Until then, however, changed the indication of Actos 15 on Actos 30 to Actos 45 for a once-a-day single dose. In the meantime, slight edema in the legs had developed, which I ascribed in advance to the phlebitis, which had already been treated before the onset of diabetes. However, a newly developed compensatory vein for the previously drawn has apparently not formed. The skin on the legs, after being burnt for years, became increasingly glassy, i.e., hard and extremely sensitive. Now she was additionally stretched from the inside by water retention and, of course, minimal injuries due to diabetes healed much more slowly. In addition, I hardly ever fit a pair of shoes. The new HA simply prescribed a dehydrating drug (HCT) and increased the dose to 25mg twice a day, although it is warned against continuous use. He came to my presumed coronary insufficiency with the prescription of a beta-blocker (ACE) without consulting a cardiologist. The shortness of breath, however, remained. Later, he switched to enalapril 20, mainly against high blood pressure. Other chronic diseases that have been with me for more than 20 years have widened. Once a year occurring forehead u. Sinusitis also appeared suddenly in the summer and remained unusually persistent and long. The first ENT doctor consulted the case with a far too low dose of antibiotic, and for the first time there was an allergic reaction that I had never had to deal with before. Sinusitis dominated my head for a good three weeks and has been on the rise ever since. The blood glucose levels derailed significantly each time, especially in the morning. A muscle tension in the back I attributed to a nocturnal chill, which may have been caused by a slipped Zudecke, but I had a good four weeks, an exceptionally painful muscle strain on the right back. A misstep on the descent from the second step of a stepladder was followed by a fall back on soft mossy turf, but as it rolled, it squeezed my right arm roughly into the right side, culminating in a six-week healed healing of a broken rib. From a ridiculous crawl on all fours to plant a garden-bed, I was unable, as a result of shortness of breath, to raise myself again, and fell on my stomach, like a fish on dry land. All shopping trips by bike regularly lead, despite adapted clothing, to torrents of sweat pouring out of all the pores of my head, as if you had turned on a faucet. – After that, I often have to recover for over an hour lying on my bed and change clothes completely. My consumption of kitchen rolls has increased dramatically in the last two years, but not by the need for kitchen work. The fragrance that accompanied me for over ten years, would rather not speak. Unfortunately, I barely smell it myself and may therefore often let me respond to it. A particularly unpleasant side effect is the coloring of body sweat. The ingested drug cocktail bleeds outright yellow in the underwear and can be bleached only by the soaking in dilute chlorine detergent for several days before cooking with the machine at all again. Another normality associated with diabetes sequelae are nerve disorders, especially on the extremities. Whenever I lie down for more than a few minutes, the numbness begins in the toes and bones of both feet. As soon as I stand and walk, the feeling subsides, regardless of any “sugar pleasure”. Since I also suffered from increased sleep disorders in previous years, often due to occupational stress, I was initially unable to identify any direct connection with Actos 45. However, I believe that especially after reading the internet I should reevaluate the context of action. Often I fall asleep with exhaustion for one to three hours, then I am back – also deep in the night

    Side effects: Nausea; Sleep disorders
  9. Darla S. Jackson says:
    3.5 rating

    Actos for Diabetes mellitus type i

    Pain in the right upper abdomen and back – was suspected shingles. Weight gain 15 kg – starting dizziness. After discontinuing Actos 45, the weeks-long discomfort disappeared. Although Actos 45 helps to reduce the blood sugar levels, but too strong side effects.

  10. Joanne A. Speer says:
    3.5 rating

    Actos for Diabetes mellitus type i

    After 9 months of taking the medicine I stop today. I’m looking for 6 months, what’s wrong with me. Sleep disorders (3-hour rhythm between sleeping and being awake), water retention in the legs, very high weight gain (30kg), back pain in the back, muscle aches and shortness of breath. I am a very agile person, have a large plot (4000m2) to manage, so with phlegmatism is not. But since November last year, I’ve noticed that I was very short of breath, all my muscles and bones hurt. Strong ankle swelling since January. Sleep disorders since September07. none of the consulting physicians could tell me anything. Neither the diabetes doctor, nor others. Cardiac ECG long-term o.B. But I did not want to accept it now. I came across this forum, have read and now it’s over with funny. From now on, I stop using this medicine. If that was the case, there will be an improvement. Thank you for reading this forum, was very helpful.

  11. Curtis T. Rafferty says:
    4.0 rating

    I was diagnosed with pneumonia in January 2009 after having pneumonia in the hospital, that I have type II diabetes. I then received metformin, initially 850 mg twice a day, and Actos 30 mg once a day in the morning. By taking Actos 30mg I have so far no side effects. I am fine. My body weight is constant between 68.5 and 70 kg.

    Side effects: No side effects
  12. John F. Gilmore says:
    4.0 rating

    Actos for Diabetes mellitus type ii

    Well tolerated, after a period of use of about 1 year switched to Actos 45, by additional intake of Sucontral (homeopathic drops) again reduced to Actos 30th

    Side effects: No side effects
  13. Lawerence S. Bolden says:
    3.5 rating

    Actos for Diabetes mellitus type ii

    I am Actoc for 6 months. At the beginning I was very satisfied, the blood value had decreased (from 8.5 to 7.3). So far, I have not paid attention to Nebeenwirkungen. I have more pain in the shoulder for a longer time, urge was not clear. Since they were slow, I could not see any connection. But in the last months have increased, 5 KILO. Also, I have off and you mild blurred vision (blurry vision) is unclear. I want to settle it now, it’s just the question of what to do next? If you have experience, please send a short mail. mfg Klinkenberg

  14. Betty J. Moniz says:
    3.0 rating

    Actos for Diabetes mellitus type ii

    I took ACTOS for about 2 months and got spasmodic kidney pain during this time and soon afterwards a shrill cough with shortness of breath and expectoration of mucus. After weaning, the kidneys were OK again, but my bronchi raged for many weeks. Now I’m just starting with Siofor 1000 and I’m alert on the side effects.

    Side effects: Difficulty in breathing
  15. Nicole M. Taylor says:
    3.0 rating

    Actos for Diabetes mellitus type ii

    Hello Good day, 3 years ago, I was switched to NovoRapid, so far well tolerated so far, however, my weight increased constantly and I sometimes got a little shortness of breath. End of May d.J. I was switched to Actos, I tolerated it very well at first, I felt much better than with NovoRapid, but gradually turned out respiratory problems to acute respiratory distress. I discontinued the medication, started NovoRapid again, but the breathing problems associated with heart stumbling continued to increase. My question? Has anyone had similar experiences?????? I would like to learn more. Sincerely, Hannah K