About Aciclovir

3.5 rating based on 30 ratings
Rating: 3.3 Reviews: 30
About Aciclovir

Aciclovir is used in infections with herpes viruses. There are several herpesviruses that cause a variety of diseases. The most well-known representative is the herpes simplex virus type I, the causative agent of the cold sore. But the chickenpox and shingles (herpes zoster) and eye infections caused by herpes viruses and genital herpes are caused by this group of viruses and can be treated with the drug.

What is the purpose of this ingredient?

  • Treat infections with herpes viruses such as cold sores, chickenpox, shingles, eye infections caused by herpes viruses (also conjunctivitis), genital herpes, severe skin infections and herpes simplex encephalitis (inflammation of the brain by herpes simplex viruses) / li>
  • Itching and mild to moderately severe pain in lip or genital herpes relieve
  • Prevent infections with varicella zoster virus or severe herpes infections in immunocompromised adults

  • Prevent recurrence of severe genital herpes infections.

This is how Aciclovir works

Below you will learn more about the fields of application and the mode of action of acyclovir.
Please also read the information on the drug groups antiviral agents, herpes, to which the active ingredient aciclovir belongs.

Areas of application of the active substance aciclovir

Aciclovir is used in infections with herpes viruses. There are several herpesviruses that cause a variety of diseases. The most well-known representative is the herpes simplex virus type I, the causative agent of the cold sore. But the chickenpox and shingles (herpes zoster) and eye infections caused by herpes viruses and genital herpes are caused by this group of viruses and can be treated with the drug.

Aciclovir is used for the relief of itching and mild to moderate pain in the form of creams mainly for the external treatment of herpes infections of the lips or genitals. For prolonged use, the active substance may prevent the recurrence of severe genital herpes infections.

For eye infections caused by herpes viruses, including conjunctivitis, there are special eye creams and ointments with the active ingredient.

The tablet form and the solution (suspension) for drinking contain higher doses of acyclovir. The 200 milligram tablets are therefore also used for the prevention and treatment of severe recurrent skin and mucous membrane infections with herpes simplex or genital herpes viruses.

A serious skin infection, such as shingles, is treated with acyclovir 400 milligrams or 800 milligrams tablets or infusions. These two forms are also approved to prevent infections with varicella-zoster viruses.

Infections caused by varicella or herpes simplex viruses often affect people with a weakened immune system. The cause of this can be either a congenital or acquired in the course of life immunodeficiency, a so-called secondary immunodeficiency. The latter may occur during immunosuppressive (immune suppressive) therapy after organ transplantation or in cancer treatment with cytostatics). In these patients with an increased risk of infection, the active ingredient can be given as a preventive acyclovir infusion or tablet.

In the treatment of dangerous herpes simplex encephalitis (inflammation of the brain by herpes simplex virus) are also infusion solutions with aciclovir used.

For the following application areas of Aciclovir , in-depth information is available:

  • shingles
  • Cold Sores
  • Herpes on the genitals
  • skin infections
  • Inflammation of the oropharynx
  • Eye infections caused by herpesviruses
  • itching
  • conjunctivitis

Action of acyclovir

Aciclovir belongs to the active ingredient group of herpes and works against herpes viruses by preventing the multiplication of viruses.

The active ingredient is a so-called prodrug (precursor). It is converted into the effective form acyclovir triphosphate only after it has entered a virus by its own enzymes. Simplified, it can be said that the virus produces its own antidote. The resulting acyclovir triphosphate inhibits the one hand, the necessary for the multiplication of the virus enzyme virus DNA polymerase. On the other hand, it is also incorporated into the genome of the virus. The wrong building block leads to the abortion of protein production and thus also the multiplication of herpes simplex viruses and varicella-zoster viruses in the affected body cells. Locally applied acyclovir has a targeted effect on affected parts of the body. Accepted acyclovir in tablet form can prevent the spread of viruses throughout the body. The earlier the application is started, the better the effect.

Aciclovir can also relieve the nerve pain associated with shingles. Which mechanism of action is responsible for this is not yet clear.

Potential Aciclovir side effects may include:

Aciclovir used to treat the following diseases:




  1. Sammie J. Marrero says:
    3.5 rating

    Aciclovir for Shingles

    It helped against the facial belt rose. However, a few weeks later I fell 11m from the roof without knowing why. 2 weeks I was in an artificial coma. During the coma, I had insane nightmares that really united the real with fantasy. I can not prove it, but suppose it was because of the drug. Incidentally, I had to take against Rheum MTX Metrotrexan and Kordison. But the nightmares (which were very real, 2 weeks seemed to me like several years and I could still write a book of a thousand pages) were a very very bad experience and it took me a lot of time to even notice where I am and which is real. I would like to know exactly if I have the drug but to prove something like that is not possible for me.

    Side effects: Nightmares
  2. Marian G. Carpenter says:
    1.0 rating

    Aciclovir for Shingles


  3. Jane J. Moreno says:
    1.0 rating

    possibly speech disorders and seizures – has anyone made similar experiences?

  4. Dennis J. Harris says:
    4.0 rating

    Aciclovir for Shingles

    I went to the doctor after noticing my skin change and he diagnosed a shingles. Until then I was fine! A little tiredness and skin redness with small bubbles were everything. He then prescribed me acyclovir with the recommendation every 5 hours one tablet. After taking the 2 tablet, I was rapidly worse. Tiredness, nausea, severe body aches and unbearable headache. The redness was also more. I was even worse on the 2nd day and I became really depressed. I was able to get into bed at about 6 pm and the sweat just went down. I drank a lot of water and had to take a painkiller to be able to sleep at all. At this time, I had taken 7 tablets at the recommended time. When I woke up in the morning, I felt a little better. I thought about it for a long time and then decided not to take it. I only took high-dose vitamins, calcium and magnesium. And I was fine, compared to the 2 days with acyclovir. NO tiredness, NO headaches just a little burning on the reddened areas, which have not become more.

    Side effects: Depressive moods; Fatigue
  5. David R. Thomas says:
    4.5 rating

    Aciclovir for Herpes genitalis

    Hello, I once had the post: Aciclovir 400 genital herpes 10 years Registered on 05.09.2012 as record 47139, written here. Now I want to supplement this contribution with possibly important information as experience report, for all people, young or old, who are dealing with –Herpes Genitales– and suffer from frequent outbreaks. Chronic Residual Herpes Genital I had some bowel movement problems / pain due to the side effects mentioned at the time, which were even more complex (bowel movement problems, e.g., burning during bowel movements and generally during the time of taking them). Then I noticed a change in sleep, so I dreamed much more during the intake times, which I did not find unpleasant. But the night scare suddenly, this was strange, I got more nightmares, where I startled at night. Now I took Orthomol Immune for 2 years, it was suggested to me as an attempt. In response to my question: Since I can not always eat balanced and therefore not so well protected, I wanted to ask if there is something that could help me here something to strengthen my defense, a kind of supplement. There I was recommended by the doctor for interiors, as attempt the Othomol immune. I started to take it, granules package. To dissolve in water. I took it and felt it would be good for me. The herpes outbreaks were (I think) less. But they still came often. Since the taste of the yarn for me and I am not a sissy, just sometime disgusting, I struggled through, in a pharmacy to ask for an alternative preparation. That was not easy, because my main wish was: something that does not taste so disgustingly disgusting when you eat it. And yet, the pharmacist found in the system a preparation, which has similar active ingredients and was offered with extra taste. Well you could say: Taste no matter, the main thing it helps. But I had the impression it does not really help and it was still disgusting while drinking. So I was recommended a direct granulate from Ortho-Expert. Small bags. You open a bag and make the granules on the tongue and it dissolves and it tastes 100% better for me. Okay, but now for the most important part of this experiment. I took it in for a few weeks, not every day, but I took it every 2nd (memory). Then I set it off. And had no herpes outbreak for several months. I went to the pharmacy gave this feedback and ordered again a pack. I was advised not to continue taking the preparation, just wait until the next outbreak returns. So that the body just works with itself again and can form something and does not always get the stuff. I listened to that. A few weeks later I got an outbreak again. Reason was great stress intrapsychisch, so more than usual, more intense just. I did not take the harbingers with me, because I did not have a long time and did not pay any attention to it: Example of the harbingers: – pulling in the penis (over days) – tingling in the penis – pulling, pain in the testicles (right egg or left egg) – Pulling in thighs (over days) – Painful lymph nodes in groin area left and right – But also lymph node pain in the armpit area (even if it is said that can not be) – Headache I would like to give this experience to all herpes genital sufferers. This preparation has positively influenced my frequency, so minimized. But it is important to eat reasonably well. A mere intake would be a bit stupid. In addition, the price-performance ratio compared to Orthomol immune is totally great, in my understanding. In a pack of granules (cranberry) are faith 15 sticks. and it costs about 15 euros. Sometimes the prices fluctuate. Well, first I thought it’s just a promotion of some kind of remedies because of the name Immune Boost. But by now I do not care about the name, it helps me and tastes also acceptable and not abnormal / nasty and it is cheap compared to the Othomol immune. To what extent the effects are different, everyone has to compare for themselves. In any case, I would recommend here to consult the doctor also, if it is taken for several months. Well and now to Fucidine ointment I can also highly recommend this highly effective ointment. It is a skin antibiotic and helps me heal really fast, even with sores on the penis (microcracks or red spots) down it is good. It helps on the outbreak on the skin and the outbreak goes away faster. Of course, at least once a day on it and do not forget the hygiene before. And also important, keep the chain with disinfecting. I think if you touch down there during a breakout and then you should not eat it

  6. Jerry L. Trombley says:
    5.0 rating

    Aciclovir for Herpes genitalis

    For 10 years I take acyclovir. I started with acyclovir 200, it did not help at some point. The thrusts were weekly. Then it was raised to Aciclovir 400. Now I think, because of the sudden hallucinations, to let it down again. But I wonder if my body has become used to it and thus acyclovir 200 may not help anymore. In the car I was last (co-driver), aggresive, saw car accident death scenes (how movies run), and was highly sensitive to foreign cars coming towards. I was highly sensitive and completely over-anxious. I swore at the driver if he did not notice how fast the others were driving, etc. These feedback came in part from the car driver, as I was acting on those during the taking time. Otherwise, it is a highly effective drug, but beware, in people with organic diseases, acyclovir 400, is certainly a powerful drug and should not be used arbitrarily and best from time to lead a thrust journal. Genital herpes is hard, but people are fighting! Build yourself, your environment especially stress free. For me, the main cause, stress from the outside, as a trigger. Certainly different for everyone, but minimizing stress can help make the relapses less. But there are also people where stress is not just minimizable, which I wish a lot of strength & amp; Courage to talk about it, especially with potential partners. Do not mess up or lie. That would be like, (hard but honestly) if someone has HIV and conceals it. All the best to you

  7. Martha M. Belanger says:
    3.5 rating

    Aciclovir for Shingles

    Abdominal pain, upset stomach, diarrhea, discomfort, inner restlessness, hot and cold at the same time, loss of appetite, mild nausea, headache

    Side effects: Anorexia; Nausea; Headache
  8. Joseph L. Monahan says:
    5.0 rating

    Aciclovir for Herpes

    After two days 5 aciclovir 400, had severe headache, severe sweating, severe fatigue, no appetite, could not sleep at night because of sweating and back and neck muscles and shoulder burn and nerve cells burn, heatblown behind my head to my face, depression, Irritability, dry lips, permanent thirst, tachycardia, now almost three weeks is over and still have the same symptoms but in a weak way. I have a feeling the drug is still in my body. I hope soon it will go away from my body because of such side effects, I can not stand anymore. P.S. never against aciclovir was poison for my body. I would never have taken it.

  9. Ashley T. Shank says:
    3.5 rating

    Aciclovir for Shingles

    I hate this drug. I have shingles in a tour. Constantly I get Zostex or aciclovir prescribed 800 and must 5 pcs. Take daily. The first 3 times of the intake I had an incredible dizziness. I was definitely not able to sleep or sleep anymore. But even here a head was enough to move and the dizziness is back. I’m taking Aciclovir for the fourth time in a year now and this time staring at hellish back pain! ! I had to be treated at Kh I had such pain. Whether it is due to the zoster or the drug no one knows. But even now after the 4th day is the horror again there. I’m nothing in Lange again. I have such hatred for the drug. If there was any possibility I would not take it anymore!

    Side effects: Back pain; Dizziness
  10. Ricardo S. Goff says:
    3.5 rating

    Aciclovir for Herpes

    Take Aciclovir 400mg Tabl. For almost 2 years now 5 xtgl. now after 18 months only 2 days my problem: I have very strong back and pelvic pain, especially in the morning. Could there be a connection?

    Side effects: Back pain
  11. Ronald T. Dunklin says:
    3.5 rating

    Aciclovir for Shingles

    Aciclovir iV get over 4 days with herpes zoster or shingles. Minimal side effects, good treatment success!

    Side effects: Back pain; Headache
  12. James P. Lemmons says:
    3.5 rating

    Aciclovir for Herpes

    First I took in the same thing 4 weeks Zostex (same active ingredient). After a week, I was always sick, I got sweats at night and have frozen in the daytime, stomach aches, dizziness, massive depression, headaches, slackness, fatigue, sleep disorders. Now I switched to acyclovir. In the beginning everything was fine except for abdominal pain. But after a week the same side effects. There are chest complaints. I’m not waiting for the depressions anymore, but I’m leaving.

  13. Mark K. Davis says:
    4.0 rating

    Aciclovir for Herpes genitalis

    Should take acyclovir for 5 days, five times a day. Have, or had to stop after the third day. This medicine did not let me sleep any more, was wet at night like a sponge and violent panic attacks made my days hell. Especially at night. Wanted to write farewell letters because I thought I would not survive the night. The only thing that got better was my lymph nodes that swelled extremely painfully in the groin area. Today is my control date, I’m curious what to do with now. I’m certainly not squeamish, have enough things already lived and taken. But these tablets are really not recommended! Had probably read the other reports before, I would certainly have spared a lot. All good

  14. Guillermo A. Lough says:
    5.0 rating

    Aciclovir for Herpes genitalis

    Hello, I got Acyclovir-ratiopharm 200 prescribed by the Dermatologist. At first I did not notice anything (1st day). Then more and more panic attacks became noticeable and my resting heart rate went up to 95 (from the 2-3 day). I have reached the last day and I have 1 tablet in front of me. The herpes, if it was because one was (findings is not yet, but strong supposition of the dermatologist) has completely subsided. But the panic that you are living through or experiencing, coupled with sleep disorder, is brutal. I just thought it goes from me and I’m going crazy but when I read the report further up I got hope. I’m really thinking about shitting on this last pill, it’s almost unbearable, constant anxiety, trembling, high heart rate and sleep disturbance. I should have treated only with ointment first. My report, greetings and all the best Felix

  15. Heather J. Fuson says:
    1.5 rating

    Aciclovir for Shingles

    With Cipramil, I can not say if it works. I do not feel well despite taking it. But that’s probably because of my illness. Actually, I just take it for safety – to have the feeling that at least I can influence something. Whether my weight gain is due to Cipramil, I can only guess! I take aciclovir for months and the only noticeable side effect is stomach problems. I had that earlier with medication revenue. But it is bearable. The constant herpes lesions were much more stressful!

    Side effects: Stomach pain
  16. Casey A. Bradley says:
    3.0 rating

    Aciclovir for Herpes genitalis

    Very good medication, if you are organic otherwise healthy. The only side effect is: I sleep deeper, dream intensely, have nightmares and now and now come hallucinations. I have anxiety in the car and am increasingly very frightened, & amp; aggressive by it. Stool problems are not that bad.

  17. Maria F. Castaneda says:
    2.0 rating

    Aciclovir for Shingles

    I have experienced panic-like anxiety and I thought I had to be instructed! It was sooooo bad, I was scared of everything and everyone. I have never experienced something like that! and I thought that it was related to me that I now suffer from depression, etc. but after I had discontinued the drug, I was suddenly well again. I will never take that again.

    Side effects: Anxiety states
  18. Rolando T. Kovar says:
    1.5 rating


    Side effects: Diarrhea
  19. Anne D. Carpenter says:
    4.0 rating

    Aciclovir 800 was prescribed to me with diagnosis of trigeminal neuralgia for cold sores. Dosage 5 times a day, 4 hours apart. I am not very well with the tablets. Diarrhea since the first day of use, nausea from the 2nd day, vomiting on the 5th day. General strong malaise. Sleep disorder, permanent hearing of noise. Repeated visit to the doctor with the advice to continue taking the tablets so that a cure can take place. Glad if the rest of the days are finally over !!

    Side effects: Diarrhea; Nausea