Mood swings effect of Amitriptyline

We have 293 consumer reports for Amitriptyline. Mood swings effect occurred in 2%.

Patients statistics on Mood swings side effect for Amitriptyline


Average weight in Lbs

Average height in Ft
5′ 6″

Average age

Amitriptyline Circle Diagram 7 consumers of 293 reported about Mood swings

  1. Jeanette A. Legrand says:
    4.5 rating

    Amitriptyline for Pain (chronic)

    Before therapy with amitriptyline, I had tension headaches lasting years (sometimes severe pain for 3-4 weeks at a time). When I arrived at the point where NIX was more, i. E. my everyday life was beyond control; The headache with painkillers can not be controlled. A neurologist then prescribed me amitriptyline (first 12.5 then 25 mg in the evening). Already a few days I felt better. Hardly any headache. That means: Before that I had severe pain for about 20 days a month. Under amitriptyline in about 3-5 days, which means a considerable improvement in the quality of life for me. Positive: You get out of the pain circulation, painkillers are reduced, the tension headaches are drastically less – that really means a lot! Negative: Despite the low dosage, I also got loose 7 kilos on the scales. This finally caused me so much frustration after 7 months of therapy that I discontinued the tablets 2 weeks ago. The pills have made me totally tired and impotent. Mainly in the morning I felt like dead, which I z.T. really bad. I was partially unable to get up. At the beginning of the therapy I had a strong dry mouth. Was really terrible; Without water next to the bed it did not work anymore. But that got better after about 2-3 months. I also had my nose closed all the time. No cold or something, but nose totally blocked. No smell possible. Otherwise I never had anything to do with it. Despite the great experience of being headache free, I had severe mental lows during the treatment, humorous, sometimes aggressive behavior (not otherwise!). Parallel occurred with me a thyroid inflammation with nodule formation and a bad compatibility of my contact lenses. Whether there is a connection – no idea. My conclusion: For me, the therapy was already worth it because I came out of my headache circulation. There is no real alternative to amitriptyline. Now I have dropped the TAbletten since 2 weeks and my headache pile up a bit more. MAl wait. My neurologist says that after Absetzén (he recommends, incidentally, a longer duration of use than 7 months) should be an improvement to before, unfortunately no disappearance. For me it would be great if only 1-2 weeks a month would have a headache. Would I do the therapy again? I believe NO! Despite slight success, the side effects (weight, depression, aggressive behavior, nightmares, dark thoughts, extreme impotence, chronic nasal congestion, dizziness, heavy sweating) are just too intense for me personally. Especially now the effects after weaning: losing weight a mental torture; extreme falling asleep, headache, irritability, sweats – hope that’s over soon. But what if I get back to the point where the headache is nothing more ???

  2. Wynona W. Shirley says:
    3.5 rating

    Amitriptyline for Depression

    I’ve been taking amitriptyline for about 4 months now after 13 years of having my depression. It took a long time for me to decide to even take any medication. Now, in retrospect, I get annoyed that I did not do it much earlier. Amitryptiline was prescribed for me because I also had (connected with my depression) a very pronounced irritable bowel syndrome and also from the stomach, most of the drugs have very poorly tolerated. Since amitriptyline is also used in irritable bowel syndrome and probably has a positive effect on the autonomic nervous system, I killed two birds with one stone. The side effects were in my beginning very pronounced with constantly very cold hands, fingers and feet, as well as numb fingers and at times a numb lip. In addition, there was ongoing fatigue and at times in the first few weeks sleep disorders with sweating and nightmares. There were also extreme mood swings and irritability. My neurologist then advised me to lower the dose once more and then slowly re-dose it. At the moment I am at 75 mg and I have to say that I have never felt better …..! The side effects are almost completely gone (except the fatigue), also my depression and the irritable bowel !!! To the weight gain described by many, I can say that I have no problems with it, but I also go to the sport 3 times a week. But yes, the increased craving for sweets I have already noticed. However, I think weight gain is not as significant as the benefits of amitriptyline treatment. At least not for me!

  3. Denice A. Sonnier says:
    3.5 rating

    I have taken Palexia 200mg, Topimarat 50mg and Amitriptyline 25mg daily for 2 years. Have had almost no pain during this time, rarely only a headache. Through the medis, I gained 15kg in time. Weekly extreme sleep problems had, my mood swings were also changing weekly. Had more language problems and word finding disorders and loss of concentration. I started dropping Palexia 4 weeks ago, it worked without problems. Have taken to replace tramadol and I am now Palexia free after 4 weeks. The Topimarat has been reduced to half, so far I have no depreciation. Next week is still the Ami. Down to 10mg.